Behavioral and Brain Function Study for Impulse Control
(SIGN Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore the relationship between different personalities, brain functions, and impulse control. Researchers will employ behavioral tasks, eye tracking, and fMRI (functional magnetic resonance imaging) brain scans to examine how individuals process rewards and manage attention. Right-handed, English-speaking participants who have used cannabis at least once may be suitable candidates. The trial seeks to understand how different information processing styles affect behavior. As an unphased trial, participants can contribute to groundbreaking research that enhances the understanding of human behavior.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are currently or have been treated with centrally acting medications in the past 6 months, except for ADHD medication.
What prior data suggests that these behavioral tasks and assessments are safe?
Research has shown that the tools used in this study, such as eye tracking, fMRI, and surveys, are generally safe for people. Eye tracking has appeared in many studies, including those involving children with ADHD, without reports of harm. Researchers commonly use fMRI scans to study brain function, and they are considered safe, though they can sometimes be uncomfortable due to noise or the need to remain still for extended periods. Surveys and questionnaires are also widely used, but they can occasionally cause emotional discomfort if the questions are sensitive. Overall, participants generally tolerate these methods well, and they are considered safe.12345
Why are researchers excited about this trial?
Researchers are excited about this trial because it explores innovative methods to understand impulse control through advanced techniques like behavioral tasks, eye tracking, and fMRI. Unlike traditional treatments that often focus on medication or therapy alone, this approach delves into the brain's functioning and behavior patterns to identify new ways to manage impulsivity. By using these cutting-edge tools, researchers hope to uncover insights into how impulsive behaviors develop and potentially pave the way for more personalized and effective interventions in the future.
What evidence suggests that these behavioral tasks and eye tracking, fMRI, and questionnaires could be effective for studying impulse control?
In this trial, participants will undergo assessments using eye-tracking, fMRI, and questionnaires to study impulse control. Research has shown that eye-tracking effectively captures behaviors related to personality traits, such as emotional reactions and self-control. Studies have found that eye-tracking data consistently reveals patterns, making it a useful tool for identifying behavioral changes over time. Similarly, brain scans (fMRI) have shown increased activity in areas related to self-control, such as the front part of the brain, indicating they can highlight changes in brain function related to self-control. Questionnaires effectively measure impulsivity and attention, often outperforming other tasks according to researchers. Together, these tools help researchers understand how people manage impulses by examining both brain activity and visible behaviors.678910
Who Is on the Research Team?
Lora Cope, PhD
Principal Investigator
University of Michigan
Are You a Good Fit for This Trial?
This trial is for emerging adults interested in understanding their personality, brain function, and behavior. It's suitable for those with or without a history of drug addiction. Participants should be willing to undergo fMRI scans, complete questionnaires and surveys, as well as perform behavioral tasks and eye tracking exercises.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Assessment
Participants undergo assessments to measure individual differences in personality, brain function, and behavior
Follow-up
Participants are monitored for safety and effectiveness after assessments
What Are the Treatments Tested in This Trial?
Interventions
- Behavioral tasks and eye tracking
- fMRI
- Questionnaires and surveys
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Michigan
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Collaborator