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Cognitive Processing Therapy for PTSD-BPD
N/A
Recruiting
Led By Candice M Monson, PhD
Research Sponsored by Palo Alto University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Current DSM-5 diagnosis of PTSD and BPD
Aged 18-65 years
Must not have
Conditions requiring medical attention to a potentially life-threatening illness (e.g., severe anorexia nervosa)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3-weeks, post-treatment/6-weeks, 3-month follow-up
Awards & highlights
Summary
This trial tests a new treatment combining Cognitive Processing Therapy with Suicide Risk Management for people with both PTSD and BPD. The goal is to provide a shorter, more effective treatment that addresses intense emotions and negative thinking patterns. The study will evaluate how well this approach works. Cognitive Processing Therapy (CPT) has been shown to be effective in reducing PTSD symptoms among survivors of sexual assault and other traumas.
Who is the study for?
This trial is for adults aged 18-65 in the Bay Area with PTSD and BPD who are willing to be recorded during sessions. It's not for those with severe comprehension issues, EU residents, life-threatening illnesses, acute mania or psychosis, or intellectual disabilities.
What is being tested?
The study tests Cognitive Processing Therapy enhanced with Suicide Risk Management (CPT+SRM) against usual treatment plus SRM. Conducted via telehealth over 12 sessions, it aims to improve PTSD-BPD symptoms by targeting emotional intensity and cognitive dysfunction.
What are the potential side effects?
Participants may experience emotional distress or discomfort when discussing trauma and mental health issues. There's also a risk of increased suicidality or self-harm which will be managed through a suicide risk protocol.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have been diagnosed with PTSD and BPD.
Select...
I am between 18 and 65 years old.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I have a severe illness that could be life-threatening.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 3-weeks, post-treatment/6-weeks, 3-month follow-up
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3-weeks, post-treatment/6-weeks, 3-month follow-up
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Borderline Symptom List 23 (BSL-23) [SELF-REPORT]
Clinician-Administered PTSD Scale for DSM-5 (CAPS-5)
Secondary study objectives
A Demographic Form [SELF-REPORT]
Acceptability of Intervention Measure (AIM)
Beck's Depression Inventory-II (BDI-II) [SELF-REPORT]
+24 moreTrial Design
2Treatment groups
Experimental Treatment
Group I: TAU + SRMExperimental Treatment1 Intervention
Participants will be randomized to teletherapy sessions with only Suicide Risk Management for PTSD-BPD which will be administered once a week for 6 weeks, for a total of 6 sessions.
Group II: CPT + SRMExperimental Treatment1 Intervention
Participants will be randomized to teletherapy sessions of Cognitive Processing Therapy + Suicide Risk Management for PTSD-BPD which will be administered twice weekly over 6 weeks, for a total of 12 sessions.
Research Highlights
Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
The most common treatments for Borderline Personality Disorder (BPD) include Dialectical Behavior Therapy (DBT), Mentalization-Based Therapy (MBT), Transference-Focused Therapy (TFT), and Cognitive Behavioral Therapy (CBT). DBT focuses on managing suicidal and dangerous behaviors, improving emotional regulation, and enhancing quality of life.
MBT helps patients observe their mental states and develop alternative perspectives, improving emotional intensity and cognitive dysfunction. TFT addresses distorted perceptions of significant others through exploration and confrontation, aiming to correct emotional and cognitive distortions.
CBT targets distorted cognitions and behaviors to improve social and emotional functioning. These therapies are crucial for BPD patients as they address core symptoms such as emotional dysregulation and cognitive distortions, which are also the focus of CPT+SRM in treating PTSD and BPD.
Find a Location
Who is running the clinical trial?
Toronto Metropolitan UniversityOTHER
91 Previous Clinical Trials
18,942 Total Patients Enrolled
2 Trials studying Borderline Personality Disorder
346 Patients Enrolled for Borderline Personality Disorder
York UniversityOTHER
63 Previous Clinical Trials
521,358 Total Patients Enrolled
3 Trials studying Borderline Personality Disorder
406 Patients Enrolled for Borderline Personality Disorder
Stanford UniversityOTHER
2,459 Previous Clinical Trials
17,494,911 Total Patients Enrolled
2 Trials studying Borderline Personality Disorder
75 Patients Enrolled for Borderline Personality Disorder
Media Library
Research Study Groups:
This trial has the following groups:- Group 1: TAU + SRM
- Group 2: CPT + SRM
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