Torso Weighting for Multiple Sclerosis

(BBTW-MS Trial)

Overseen By Evan Pucillo

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of St. Augustine for Health Sciences

Disqualifiers: Concurrent neurological disorder, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 3

40 Participants Needed

Trial Summary

What is the purpose of this trial?

Rationale: The Balance-Based Torso-Weighting (BBTW) is a patented evaluation system that uses strategic placement of small or lightweight weights on the trunk to improve balance and stability. BBTW has been found to improve the upright mobility of people with multiple sclerosis, however the mechanism underlying the improvement of balance and gait is still unknown.1-2 Purpose: The purpose of this study is to investigate the immediate effects of BBTW on muscle activation of tibialis anterior and gastrocsoleus and sway using electromyography and force plates during balance tests in people with MS and healthy controls?

Research Team

Amie Marie F Jasper, DPT, PhD

Principal Investigator

USAHS

Eligibility Criteria

This trial is for individuals with Multiple Sclerosis (MS) or Systemic Sclerosis. It aims to explore how torso weighting affects muscle activation during balance tests. Participants should be able to perform balance tests and have no conditions that would interfere with the study.

Inclusion Criteria

* self-reported diagnosis of multiple sclerosis (MS)

* able to communicate in English

* able to provide informed consent

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Baseline Assessment

Initial measurements of muscle activation and postural sway using EMG and force plates

1 day

1 visit (in-person)

Intervention

Participants undergo balance tests with and without balance-based torso weighting

1 day

1 visit (in-person)

Follow-up

Participants are monitored for any immediate effects post-intervention

1 day

1 visit (in-person)

Treatment Details

Interventions

• Balance-Based Torso-Weighting

Trial Overview The study is testing Balance-Based Torso-Weighting (BBTW), a method where weights are placed on the torso to potentially improve balance. The immediate effects on muscle activity and stability will be measured using special equipment in people with MS and without.

Participant Groups

Group I: Multiple Sclerosis Arm Experimental Treatment 1 Intervention

Without and with balance-based torso weighting

Group II: Healthy Control Arm Active Control 1 Intervention

Without and with balance-based torso weighting

Who Is Running the Clinical Trial?

University of St. Augustine for Health Sciences

Lead Sponsor

Trials

8

Recruited

450+