Compassion-Focused Cognitive Behavioural Therapy for Psychosis
(REFLECT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The current study is an open-label, proof-of-concept, pilot trial examining the feasibility, safety, and preliminary efficacy of a 6-week group therapy intervention targeting core beliefs related to symptoms of psychosis. Core beliefs are theorized to be central to the development and maintenance of psychosis and other mental health conditions; however, research on how to address this key mechanism in psychosis is rarely directly studied.
The primary questions it aims to answer include:
1. Is targeting core beliefs in a technology-supported remote group therapy format safe and feasible?
2. Does targeting core beliefs result in measurable change in core beliefs?
The investigators hypothesize that this intervention will be safe and feasible, and that we will see improvements in maladaptive core beliefs.
Secondary outcomes include changes in positive and negative symptoms, personal recovery, and whether there are improvements in other cognitive mechanisms, like cognitive biases, and behavioural mechanisms, like safety behaviours.
As this is an open pilot trial, there is no comparison group. All participants will have the opportunity to participate in the group therapy intervention.
Participants will be asked to take part in four assessment visits: screening (Day 1), baseline (pre-intervention; Day 1-14), post-intervention (Weeks 7-9), and a three-month follow-up (Weeks 19-21). The intervention under investigation is a 6-week group therapy intervention consisting of weekly 2-hour sessions delivered via video conferencing, with weekly home practice assignments delivered and completed remotely.
Who Is on the Research Team?
Micheal W Best, PhD
Principal Investigator
University of Toronto
Sean A Kidd, PhD
Principal Investigator
University of Toronto
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline
Pre-intervention assessments are conducted
Treatment
Participants undergo a 6-week group therapy intervention with weekly 2-hour sessions delivered via video conferencing
Post-intervention
Assessments conducted to evaluate changes post-treatment
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- REFLECT
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
As there is only one arm in this open-label, proof-of-concept study, all participants enrolled in this study will have the opportunity to complete a six-week group intervention consisting of integrated skills and strategies within a CBTp framework.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Toronto
Lead Sponsor
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