50 Participants Needed

Genomic Risk for Retroperitoneal Liposarcoma

AV
Overseen ByAnthony Villano, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Fox Chase Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores why tumors often return in patients with retroperitoneal liposarcoma, a type of cancer in the abdomen. Researchers aim to determine if normal-looking abdominal fat contains hidden genetic changes that cause cancer recurrence. During tumor removal surgery, participants will provide samples of their abdominal fat for analysis. Eligible participants have been diagnosed with retroperitoneal liposarcoma and are planning surgery for its removal. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that could enhance future cancer treatments.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

Researchers are excited about this trial because it focuses on the genomic risk in retroperitoneal sarcoma, particularly retroperitoneal liposarcoma. Unlike traditional treatments like surgery, chemotherapy, or radiation, which aim to physically remove or destroy the tumor, this trial investigates the genetic factors that could influence the development and recurrence of the cancer. By understanding these genomic risks, there is potential to personalize treatment strategies, improve surgical outcomes, and reduce recurrence rates. This approach represents a shift towards more tailored and effective treatment plans for patients with retroperitoneal sarcoma.

Are You a Good Fit for This Trial?

Inclusion Criteria

My tests show I likely have a fatty tumor in my abdomen area.
I am scheduled for surgery to remove my cancer.
I have signed the consent form for this study.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Surgical Resection

Participants undergo surgical resection of their retroperitoneal liposarcoma tumor

1 day
1 visit (in-person)

Genetic Analysis

Retroperitoneal fat is sampled and subjected to genetic analyses to identify predisposing factors for liposarcoma

Ongoing throughout study

Follow-up

Participants are monitored for recurrence and genetic changes in retroperitoneal fat

3 years

What Are the Treatments Tested in This Trial?

Interventions

  • Biospecimen sample collection
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Cohort 1Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Fox Chase Cancer Center

Lead Sponsor

Trials
236
Recruited
39,300+
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