50 Participants Needed

Genomic Risk in Retroperitoneal Sarcoma

AV
Overseen ByAnthony Villano, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Fox Chase Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The protocol intends to explore the biology which may underlie recurrences of retroperitoneal liposarcoma. Surgery remains the only curative intent intervention for this disease. Often, tumors recur in locations within the retroperitoneum remote from the original primary tumor. This study hypothesizes that normal appearing retroperitoneal fat actually harbors underlying genetic changes which predispose to development of future liposarcoma. To accomplish this goal, retroperitoneal fat is sampled from quadrants within and remote from the primary tumor and is subsequently subjected to genetic analyses looking for such predisposing factors.

Are You a Good Fit for This Trial?

Inclusion Criteria

I have signed the consent form for this study.
My tests show I likely have a fatty tumor in my abdomen area.
I am scheduled for surgery to remove my cancer.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Surgical Resection

Participants undergo surgical resection of their retroperitoneal liposarcoma tumor

1 day
1 visit (in-person)

Genetic Analysis

Retroperitoneal fat is sampled and subjected to genetic analyses to identify predisposing factors for liposarcoma

Ongoing throughout study

Follow-up

Participants are monitored for recurrence and genetic changes in retroperitoneal fat

3 years

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Cohort 1Experimental Treatment1 Intervention
The entire study is a singular cohort of patients with retroperitoneal liposarcoma (index or recurrent) who undergo surgical resection of their tumor.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Fox Chase Cancer Center

Lead Sponsor

Trials
236
Recruited
39,300+
Unbiased ResultsWe believe in providing patients with all the options.
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