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Motivational Interviewing + Air Cleaners for COPD (MOVE-COPD Trial)

N/A
Recruiting
Led By Nadia N Hansel, MD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age ≥ 40 years
Physician diagnosis of COPD
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 3 month and 6 months post-randomization
Awards & highlights

MOVE-COPD Trial Summary

This trial will test whether reducing indoor air pollution for smokers with COPD will improve their respiratory outcomes.

Who is the study for?
The MOVE COPD trial is for current smokers over 40 years old with a physician's diagnosis of moderate to severe COPD. Participants must have smoked the equivalent of at least 10 packs of cigarettes per year and not enforce a smoking ban in their homes. They cannot have other chronic lung diseases, live outside their home, plan to move during the study period, or be on long-term systemic corticosteroids.Check my eligibility
What is being tested?
This study tests if using active HEPA air cleaners and motivational interviewing can improve respiratory health in smokers with COPD by reducing indoor air pollution. It's a randomized controlled trial where some participants will receive sham (fake) air cleaners as a comparison.See study design
What are the potential side effects?
Since this trial involves non-medical interventions like air cleaners and counseling sessions, there are no direct side effects from medications or procedures. However, any changes in behavior or environment may indirectly affect participants' well-being.

MOVE-COPD Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am 40 years old or older.
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My doctor has diagnosed me with COPD.
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My lung condition is moderate to very severe based on breathing tests.

MOVE-COPD Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 3 month and 6 months post-randomization
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3 month and 6 months post-randomization for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in COPD health status
Change in Dyspnea as assessed by the University of California San Diego Shortness of Breath Questionnaire (SDSOBQ)
Change in Quality of Life
Secondary outcome measures
Change in Dyspnea as assessed by modified medical research Council questionnaire(mMRC)
Change in aggregate Health Care Utilization (number of episodes reported due to COPD-related exacerbation)
Lung Function as assessed by Forced Expiratory Volume in 1 second (FEV1%)
Other outcome measures
Change in Markers of inflammation in induced sputum (neutrophils count differential)
Change in Markers of oxidative stress in urine (8-isoprostane)
Change in Systemic markers of inflammation in serum (C-reactive protein)
+1 more

MOVE-COPD Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Active TreatmentActive Control2 Interventions
The active treatment arm will receive two portable active HEPA air cleaners as well as 4 sessions of phone based motivational interviewing to support a home smoking ban and SHS reduction (in addition to the smoking cessation counseling received by all study participants).
Group II: Control ArmPlacebo Group1 Intervention
Homes in the control group will receive Sham air cleaners that have the internal HEPA filter removed, but which will run normally, including similar noise, airflow and overall appearance compared to active air cleaners, thus blinding participants to filter status. The control arm will not receive phone based motivational interviewing to support a home smoking ban and SHS reduction, they will receive only smoking cessation counseling.

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,260 Previous Clinical Trials
14,820,630 Total Patients Enrolled
Nadia N Hansel, MDPrincipal InvestigatorJohns Hopkins University

Media Library

Active HEPA Air Cleaner Clinical Trial Eligibility Overview. Trial Name: NCT03658538 — N/A
Chronic Obstructive Pulmonary Disease Research Study Groups: Control Arm, Active Treatment
Chronic Obstructive Pulmonary Disease Clinical Trial 2023: Active HEPA Air Cleaner Highlights & Side Effects. Trial Name: NCT03658538 — N/A
Active HEPA Air Cleaner 2023 Treatment Timeline for Medical Study. Trial Name: NCT03658538 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are we recruiting people for this research project at this time?

"The study, which was originally posted on June 3rd, 2019, is still recruiting patients according to the information on clinicaltrials.gov. The date of the last update was June 17th, 2022."

Answered by AI

Who else is applying?

What state do they live in?
Pennsylvania
How old are they?
65+
What portion of applicants met pre-screening criteria?
Met criteria

How responsive is this trial?

Typically responds via
Email
Recent research and studies
clinicaltrials.govStudy
Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD)
2019. "Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03658538.
All > Copd
~3 spots leftby Jun 2024
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