Laryngoscopy Methods for Neonatal Respiratory Distress Syndrome

(VID LISA Trial)

PI
Overseen ByPrincipal Investigator, MD
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: University of Texas Southwestern Medical Center
Must be taking: Surfactant
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Many preterm babies born between 22-28+6 weeks' estimated gestational age (EGA) need surfactant, a medicine that helps the lungs. The goal of the study is to compare the use of video-based visualization to direct visualization during a procedure called less invasive surfactant administration (LISA). The main questions the study aims to answer are: 1) does one method of visualization have a increased rate of giving the medicine successfully on the first attempt? 2) what benefits are there of each method?

Who Is on the Research Team?

CM

Chokshi, MD

Principal Investigator

UT Southwestern

SR

Shalini Ramachandran, MD

Principal Investigator

UT Southwestern

Are You a Good Fit for This Trial?

Inclusion Criteria

My baby was born at or before 28 weeks and needed CPAP and surfactant soon after birth.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants undergo less invasive surfactant administration using either video or direct laryngoscopy

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after surfactant administration

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Direct Laryngoscopy
  • Video Laryngoscopy

How Is the Trial Designed?

2

Treatment groups

Active Control

Group I: Video LaryngoscopyActive Control1 Intervention
Group II: Direct LaryngoscopyActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Texas Southwestern Medical Center

Lead Sponsor

Trials
1,102
Recruited
1,077,000+