Guideline-Adherent Care for Knee Pain
(knEE-CAPP Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether a specific physical therapy approach can better manage knee pain in military Service members compared to regular care. The goal is to determine if this treatment improves knee function and reduces the need for pain medication over time. Participants will follow either a special guideline-based treatment (Clinical Practice Guideline-adherent Care) or standard physical therapy. Service members with ongoing knee pain during activities like sitting, squatting, or running might be suitable for this trial. As an unphased trial, this study offers Service members the chance to contribute to research that could enhance knee pain management strategies.
What prior data suggests that this Clinical Practice Guideline-adherent care is safe for managing patellofemoral pain?
Research shows that following specific guidelines for treating patellofemoral pain (pain around the kneecap) can lead to better results. These guidelines have improved care for people with knee problems, and evidence supports their effectiveness.
Physical therapy treatments are generally well-tolerated, with most people not experiencing serious side effects. The guidelines ensure consistent care based on the best available evidence, making it both safe and effective.
This trial aims to compare care that follows these guidelines with usual physical therapy care. Both types of physical therapy typically carry a low risk of side effects, so participants can feel confident about the safety of these treatments.12345Why are researchers excited about this trial?
Researchers are excited about the Clinical Practice Guideline-adherent Care for knee pain because it offers a more personalized approach to treatment. Unlike the usual care, which relies on routine physical therapy evaluations, this method uses a specific decision tree to tailor treatments based on individual impairments. This could lead to more effective and efficient management of knee pain, addressing the unique needs of each patient rather than applying a one-size-fits-all therapy.
What evidence suggests that this Clinical Practice Guideline-adherent care is effective for patellofemoral pain?
This trial will compare Clinical Practice Guideline-adherent Care with Usual Care for knee pain. Research has shown that following specific treatment guidelines for knee pain, known as patellofemoral pain (PFP), can improve knee function and reduce pain. Studies have found that this approach can also boost confidence in performing activities related to military duties. Those who receive guideline-based care may use fewer healthcare services and require less pain medication over time. Conversely, many who receive standard care do not experience improvement in their condition after three months. Overall, evidence suggests that guideline-based care could be a more effective way to manage PFP.12346
Who Is on the Research Team?
Sara R Gorczynski, PT, DPT
Principal Investigator
United States Naval Medical Center, San Diego
Are You a Good Fit for This Trial?
This trial is for active-duty military members with knee pain known as Patellofemoral Pain Syndrome. Participants must have specific symptoms like pain during activities that put weight on a bent knee and be available for treatment sessions within 6 weeks of joining the study.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Randomization and Baseline Assessment
Participants are randomized to receive either CPG-adherent care or usual care and complete baseline assessments
Treatment
Participants receive physical therapy according to their group assignment (CPG-adherent care or usual care)
Follow-up
Participants are monitored for safety and effectiveness after treatment, with assessments at 3, 6, and 12 months
What Are the Treatments Tested in This Trial?
Interventions
- Clinical Practice Guideline-adherent Care
- Usual Care
Trial Overview
The study compares two types of physical therapy: one strictly follows Clinical Practice Guidelines (CPG) for treating knee pain, while the other uses usual care methods. The goal is to see if CPG-adherent care improves knee function, reduces pain, and lowers healthcare costs over time.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants randomized to receive CPG-adherent care will first receive a comprehensive clinical examination following the PFP CPG Decision Tree guidelines. Their treatment plan of care will correspond to any and all impairment subcategories, as defined by the PFP CPG.
All participants randomized to the UC group will receive routine physical therapy evaluations and treatments in the outpatient physical therapy clinics at each participating military treatment facility, at the discretion of the staff physical therapist.
Find a Clinic Near You
Who Is Running the Clinical Trial?
United States Naval Medical Center, San Diego
Lead Sponsor
Sara Gorczynski
Lead Sponsor
Chapman University
Collaborator
University of Pittsburgh
Collaborator
Naval Hospital Camp Pendleton
Collaborator
Brooke Army Medical Center
Collaborator
Womack Army Medical Center
Collaborator
The Geneva Foundation
Collaborator
Henry M. Jackson Foundation for the Advancement of Military Medicine
Collaborator
Naval Hospital Camp Pendleton
Collaborator
Citations
1.
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov/41273076/?utm_source=FeedFetcher&utm_medium=rss&utm_campaign=None&utm_content=0eCb9nnAWs45PldwPaO9KAln6Yz_PSfxZDC9OxsAN2K&fc=None&ff=20251126213550&v=2.18.0.post22+67771e2Protocol for a Multisite, Parallel-Arm Randomized Clinical ...
Objective: The Evaluating the Effectiveness of Clinical practice guideline Adherence for Patellofemoral Pain (knEE-CAPP) trial assesses whether ...
2.
academic.oup.com
academic.oup.com/ptj/advance-article-pdf/doi/10.1093/ptj/pzaf138/65467778/pzaf138.pdfEvaluating the Effectiveness of Clinical Practice Guideline ...
We hypothesize CPG-adherent care will produce greater improvements in knee function, pain, and perceived confidence with performing duty-related ...
Evaluating the Effectiveness of Clinical Practice Guideline ...
Can a CPG-adherent care approach to PFP management improve short- and long-term knee function, pain, and confidence with completing duty-related ...
Patellofemoral Pain
In the individuals who received medical advice from a physician, 68% reported no improvement after 3 months, and 54% reported no improvement ...
5.
app.trialscreen.org
app.trialscreen.org/trials/evaluating-effectiveness-clinical-practice-guideline-adherence-patellofemoral-trial-nct06665204Evaluating the Effectiveness of Clinical Practice Guideline ...
Participants may experience improved knee function, reduced pain, increased confidence in performing duty-related activities, and reduced healthcare resource ...
6.
umimpact.umt.edu
umimpact.umt.edu/en/publications/differences-in-content-of-care-and-outcomes-between-a-clinical-prDifferences in content of care and outcomes between a ...
T1 - Differences in content of care and outcomes between a clinical practice guideline adherent program and usual care for patellofemoral pain.
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