HPV Self-Collection for Cervical Cancer Screening
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether offering an HPV self-collection test at Mayo Clinic Express Care clinics can increase cervical cancer screening rates and improve follow-up care. Regular screening and treatment of early changes can often prevent cervical cancer, yet many people are overdue for screenings. Participants will either receive the usual care, involving an in-office exam, or try the self-collection method. Women overdue for cervical cancer screening by at least a year, without symptoms like pelvic pain or unusual bleeding, might be suitable for this trial.
As an unphased study, this trial provides a unique opportunity to contribute to innovative screening methods that could enhance accessibility and convenience for many.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you are using chronic immunosuppressant medication, you would not be eligible to participate.
What prior data suggests that HPV self-collection is safe for cervical cancer screening?
Research has shown that collecting one's own sample for HPV testing is safe and easy to handle. In studies, over 80% of women found this method acceptable, with many stating it was more convenient and less embarrassing than traditional methods. Most women also found it equally or less stressful compared to samples collected by a doctor.
The FDA has approved HPV self-collection, confirming its safety. Many clinics already use this method, so it is not entirely new. Overall, collecting one's own sample for HPV testing appears to be a safe choice for women considering this screening method.12345Why are researchers excited about this trial?
Researchers are excited about HPV self-collection for cervical cancer screening because it empowers individuals to take charge of their health by collecting samples themselves, potentially increasing screening accessibility and participation. Unlike traditional methods that require a visit to a healthcare provider for a Pap smear or HPV test, this method allows for more privacy and convenience, which can be particularly beneficial for those with limited access to healthcare facilities. By making screening easier and more accessible, HPV self-collection could lead to earlier detection and treatment of cervical cancer, ultimately improving outcomes for more people.
What evidence suggests that HPV self-collection is effective for cervical cancer screening?
This trial will compare HPV self-collection with usual care for cervical cancer screening. Studies have shown that when women collect their own samples for HPV testing, the number of women screened for cervical cancer increases significantly, especially among those overdue for screening. Research indicates that mailing self-collection kits more than doubled participation in cervical cancer screening, particularly among women who had never been screened or were not screened regularly. Most women found self-collection more convenient and less embarrassing than traditional tests conducted by a healthcare provider. This method is also considered cost-effective, making it accessible to many. Overall, HPV self-collection offers a promising way to boost cervical cancer screening rates.56789
Who Is on the Research Team?
Kathy L. Maclaughlin, MD
Principal Investigator
Mayo Clinic
Are You a Good Fit for This Trial?
This trial is for individuals due for cervical cancer screening. It's testing if offering HPV self-collection at clinics with extended hours increases the number of people getting screened and following up on care.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive an invitation to schedule and complete cervical cancer screening via HPV self-collection at an Express Care clinic or choose usual care with their primary care team
Follow-up
Participants are monitored for follow-up of abnormal results obtained by self-collection or clinician-collection
What Are the Treatments Tested in This Trial?
Interventions
- HPV Self-Collection
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor