70 Participants NeededMy employer runs this trial

Inulin Supplementation for Obesity

BK
Overseen ByBryant Keirns, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The investigators seek to better understand how a single high-fat meal impacts gut, immune, and vascular outcomes in individuals with "metabolically healthy obesity" (obesity and largely normal cardiometabolic profile) and "metabolically healthy normal-weight individuals." Second, the investigators seek to understand how a prebiotic fiber (inulin) impacts gut, immune, and vascular outcomes in individuals with "metabolically healthy obesity."

Who Is on the Research Team?

BK

Bryant Keirns, PhD

Principal Investigator

Ball State University

Are You a Good Fit for This Trial?

Inclusion Criteria

* Have 0-1 risk factors based on blood pressure, blood sugar, triglycerides, and HDL-cholesterol ("good cholesterol").
I have not been diagnosed with heart disease or type 2 diabetes.
I do not have any chronic inflammatory or digestive diseases.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks
1 visit (in-person)

Meal Trial

Participants complete a meal trial involving a high-fat meal and multiple blood sample collections to assess various biomarkers.

1 day
1 visit (in-person)

Intervention

Participants receive 6 weeks of supplemental inulin or placebo with assessments at 2-, 4-, and 6-weeks.

6 weeks
3 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the intervention.

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Inulin

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Metabolically Healthy Obesity GroupExperimental Treatment3 Interventions
Group II: Metabolically Healthy Normal Weight GroupActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Ball State University

Lead Sponsor

Trials
10
Recruited
670+