Exercise for Childhood Obesity

Overseen By Jordan Sill, MD

Age: < 65

Sex: Any

Trial Phase: Academic

Sponsor: Children's Hospital Medical Center, Cincinnati

Disqualifiers: Physician judgement, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

110 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This study is for individuals who have a BMI that is at or above the 95th percentile and are participating in the Cincinnati Children's Hospital Healthworks! Structured weight loss program. The main reason for this research study is to determine how exercise affects an individual's high level of lipids (fats) in their blood and how well their blood vessels function.

Are You a Good Fit for This Trial?

This trial is for young individuals with obesity, specifically those who have a BMI at or above the 95th percentile and are already part of Cincinnati Children's Hospital Healthworks! weight loss program. The study aims to understand how exercise impacts blood fat levels and blood vessel health in these youths.

Inclusion Criteria

I speak English or Spanish.

I am between 10 and 20 years old.

I am considered obese based on my BMI.

Exclusion Criteria

Physician judgement about inability to finish the protocol

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Assessment

Participants undergo baseline assessments including Laser flow Doppler test and Veggie Meter readings

1 week

1 visit (in-person)

Intervention

Participants engage in a structured weight loss program with exercise, wearing a Garmin Vivosmart tracker for one week at a time, three times during the study

6 months

Multiple visits (in-person and virtual)

Follow-up

Participants are monitored for changes in triglyceride levels and perfusion units, with assessments at 6 months

6 months

1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

• Exercise Program

Trial Overview

The intervention being studied is an Exercise Program designed to assess its effects on lipid profiles (fats in the blood) and endothelial function (how well blood vessels work) among obese children and adolescents.

How Is the Trial Designed?

Group I: Healthworks! Structured Weight Loss Participants Experimental Treatment 1 Intervention

Participants who are already participating in the Healthworks! structured weight loss program who are between the ages of 10-20 years old.

Who Is Running the Clinical Trial?

Children's Hospital Medical Center, Cincinnati

Lead Sponsor

Trials

844

Recruited

6,566,000+