Biobank Collection for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to collect and study tissue and blood samples from cancer patients over time. Researchers hope to understand how cancer changes during treatment. This study targets patients with certain advanced cancers, such as stage IV colorectal or lung cancer, who are either starting a new treatment or continuing with existing ones. Participants should not be on experimental treatments outside of standard care.
As a Phase 2 trial, this research measures the treatment's effectiveness in an initial, smaller group, offering participants a chance to contribute to important findings.
Do I have to stop taking my current medications for the trial?
The trial does not specify if you need to stop taking your current medications. However, you cannot participate if you are on a non-standard treatment in another trial, and you may need to switch from certain blood thinners like warfarin to alternatives like low molecular weight heparin.
Why are researchers excited about this trial?
Researchers are excited about the "Cancer Moonshot Biobank" trial because it aims to better understand cancer progression and treatment response by collecting and analyzing a wide range of biospecimens, including tissue, blood, bone marrow, and cerebral spinal fluid, over time. Unlike standard treatments that focus solely on attacking cancer cells, this approach emphasizes a comprehensive understanding of cancer biology, which could lead to more personalized and effective treatment strategies. By continuously gathering data and samples, researchers hope to uncover critical insights about how cancers evolve and respond to therapies, potentially paving the way for breakthroughs in cancer management and precision medicine.
Who Is on the Research Team?
Lyndsay N Harris
Principal Investigator
National Cancer Institute (NCI)
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Biospecimen Collection
Collection of tissue and blood samples at baseline and during disease progression, including bone marrow and cerebral spinal fluid for hematological malignancies
Imaging and Data Collection
Patients may undergo CT, PET/CT, MRI, and paracentesis; medical records are reviewed and data is collected
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Biospecimen Collection
Find a Clinic Near You
Who Is Running the Clinical Trial?
National Cancer Institute (NCI)
Lead Sponsor