38 Participants Needed

Immunotherapy for Cancer

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Masonic Cancer Center, University of Minnesota
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines whether the SALSA tool can detect cognitive side effects from immunotherapy earlier than usual methods. It focuses on individuals preparing to start CAR-T therapy, a cancer treatment. Researchers will monitor participants' stress, mood, language, and speech for changes. Those planning to undergo CAR-T therapy for cancer and fluent in English might be suitable candidates. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance early detection of cognitive side effects in cancer treatments.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

Researchers are excited about the SALSA approach for cancer treatment because it offers a novel way to understand the psychological and emotional factors influencing patient health. Unlike traditional cancer treatments that primarily focus on targeting cancer cells through chemotherapy, radiation, or surgery, SALSA examines stress, affect, and language patterns, which could provide insights into how these factors impact treatment outcomes. By analyzing speech and emotional responses, researchers hope to uncover new ways to tailor personalized therapies and improve overall patient care. This method could pave the way for integrating psychological assessments into standard cancer care, potentially enhancing the effectiveness of existing treatments.

Who Is on the Research Team?

VB

Veronika Bachanova

Principal Investigator

University of Minnesota Masonic Cancer Center

Are You a Good Fit for This Trial?

Inclusion Criteria

I am scheduled for CAR-T cell therapy as an inpatient for my cancer.
I am fluent in English, either in writing or speaking.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Observational

Patients complete SALSA and ICE assessments and have their medical records reviewed

18 months

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Stress, Affect, Language and Speech Analysis (SALSA)

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: ObservationalExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Masonic Cancer Center, University of Minnesota

Lead Sponsor

Trials
285
Recruited
15,700+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+