6 Participants NeededMy employer runs this trial

Decreased Step Count for Sedentary Lifestyle

KJ
Overseen ByKevin J Gries, PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Concordia University Wisconsin
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how the number of steps taken before exercising can affect exercise benefits. Researchers are testing whether taking fewer than 5,000 steps or more than 8,500 steps the day before exercise alters its impact on health. The trial seeks healthy individuals without chronic illnesses who do not use metabolism-related medications or tobacco. As an unphased trial, it offers a unique opportunity to contribute to understanding how daily activity influences exercise benefits.

Will I have to stop taking my current medications?

If you are taking medications related to metabolism, like statins, metformin, or GLP-1 agonists, you cannot participate in this trial. The protocol does not specify about other medications, so it's best to discuss with the trial team.

What prior data suggests that this protocol is safe for participants?

Research has shown that sitting for long periods can increase the risk of diseases like diabetes, heart disease, and some cancers. However, the effects of reducing daily steps on the benefits of exercise remain unclear. Past studies have not directly addressed the safety of intentionally walking less before exercising.

This trial is labeled as "Not Applicable" for phase, indicating it is a behavioral study rather than one testing a new drug or medical device. Such studies typically involve lower safety risks. The researchers aim to understand how lifestyle choices affect health, rather than testing potentially harmful treatments. While specific safety data on walking less is unavailable, the study's nature suggests minimal risk to participants.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores how varying daily step counts might impact sedentary lifestyles differently. Unlike conventional approaches that focus on increasing physical activity, this trial investigates if maintaining a low step count on the day before exercise can influence outcomes. By examining both low and high step count strategies, researchers hope to determine the most effective way to encourage long-term activity improvements. This trial could offer new insights into optimizing exercise routines, which might lead to innovative strategies for tackling sedentary behavior.

What evidence suggests that this trial's treatments could be effective?

This trial will compare the effects of different step counts on health outcomes. Research has shown that walking fewer than 4,000 steps a day can increase health risks. In this trial, one group will maintain a step count of less than 5,000 steps the day before exercise, while another group will exceed 8,500 steps. Studies have found that walking more, up to about 10,000 steps daily, reduces the risk of heart disease and early death. For every additional 2,000 steps taken, the risk of heart problems drops by 10%. Even small increases in daily steps can significantly improve health. Regular walking, regardless of the number of steps, enhances heart health and aids in weight control.678910

Are You a Good Fit for This Trial?

This trial is for adults aged 18 to 30 who are generally healthy. People outside this age range or with certain health conditions may not be able to participate.

Inclusion Criteria

I am between 18 and 30 years old.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Pre-exercise Activity Monitoring

Participants are monitored for their activity levels, either <5,000 steps or >8,500 steps the day prior to exercise

1 day

Exercise and Sample Collection

Participants perform exercise, and blood samples are collected before and immediately after exercise for proteomic and metabolomic analysis

1 day

Follow-up

Participants are monitored for safety and effectiveness after exercise

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Decreased step count

Trial Overview

The study looks at how reducing daily steps (being less active) affects the body's response to exercise the next day. Participants will have their activity levels changed and then do exercise tests.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: <5,000 steps the day prior to exerciseExperimental Treatment1 Intervention
Group II: >8,500 steps the day prior to exericseActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Concordia University Wisconsin

Lead Sponsor

Trials
5
Recruited
210+

Citations

Daily Step Counts for Measuring Physical Activity Exposure ...

Compared with the baseline step count, each 2,000 daily steps increment up to 10,000 steps was associated with a 10-percent lower cardiovascular event rate.

Step Counter Use and Sedentary Time in Adults - PMC - NIH

This meta-analysis shows that among adults, step counter use was associated with a small but significant overall effect in reducing sedentary ...

Should we measure exercise in minutes or steps?

A new study suggests that both step-count and time-based exercise goals are equally effective in reducing risks of heart disease and early death.

Limitations of Daily Step Count for Assessing Health in ...

Background/Objectives: This study explored the association between daily step count (DSC) and health outcomes in older adults in Spain.

It Doesn't Matter How Much Time You Sit – New Study ...

Each extra step taken, up to approximately 10,000 steps daily, decreases the likelihood of mortality and cardiovascular disease (CVD), ...

6.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/40713949/

Daily steps and health outcomes in adults: a systematic ...

An inverse linear association was found for cardiovascular disease mortality, cancer incidence, cancer mortality, type 2 diabetes incidence, and ...

Around 10000 steps a day may counteract health risks ...

Previous studies have shown an association between greater daily step count and lower levels of death and CVD, and separate studies have linked ...

The association between daily step count and all-cause and ...

A 1000-step increment was associated with a 15% decreased risk of all-cause mortality (HR 0.85; 95% CI 0.81–0.91, P < 0.001), while a 500-step ...

A Sedentary Lifestyle Is Linked to Functional Decline, But ...

Research shows that being sedentary for long periods of time increases risk for diabetes, heart disease, some cancers and death. However, less is known about ...

Study Reveals The Optimal Number of Daily Steps to Offset ...

"Accruing between 9,000 and 10,000 steps a day optimally lowered the risk of mortality and incident CVD among highly sedentary participants.".