Cue Reactivity for Marijuana and Tobacco Use

(MATEY Trial)

Overseen By Elizabeth Aston, PhD

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Brown University

Disqualifiers: Pregnancy, Breastfeeding, Heavy alcohol, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 5

What You Need to Know Before You Apply

What is the purpose of this trial?

The multi session experimental study aims to determine dual use patterns of marijuana and tobacco by assessing the impact of price and availability of marijuana and tobacco using a cross price elasticity of demand task. The study will recruit 120 non-treatment seeking emerging young adults (18-25 years) who smoke marijuana and tobacco.

Are You a Good Fit for This Trial?

This study is for young adults aged 18-25 who regularly use both marijuana and tobacco. Participants should smoke tobacco at least once a week and marijuana four times a month, having done so for the past six months. They must buy their own supplies and be proficient in English.

Inclusion Criteria

I have bought tobacco and marijuana for myself in the last 6 months.

I am between 18 and 25 years old.

I have been smoking cigarettes at least once a week for the past six months.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

1 visit (in-person)

Experimental Sessions

Participants complete 4 in-person sessions including cross-cue reactivity sessions, self-report measures, and a qualitative exit interview

4 weeks

4 visits (in-person)

Follow-up

Participants are monitored for changes in self-reported cannabis and tobacco craving

40 days

What Are the Treatments Tested in This Trial?

Interventions

• Cue Reactivity

Trial Overview

The trial examines how price changes and availability of marijuana and tobacco affect usage patterns among dual users. It involves multiple sessions where participants' responses to these variables are measured using behavioral economic tasks.

How Is the Trial Designed?

Group I: Cue Reactivity Experimental Treatment 1 Intervention

Participants will be exposed to neutral followed by cannabis or tobacco cues in a fixed sequence while they answer questions about their subjective state. The cues will include everyday items (e.g., eraser) and cannabis-related items (e.g., lighter).

Who Is Running the Clinical Trial?

Brown University

Lead Sponsor

Trials

480

Recruited

724,000+

National Institutes of Health (NIH)

Collaborator

Trials

2,896

Recruited

8,053,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+