Patient Derived Preclinical Models

Recruiting at 1 trial location

Overseen By Tanya M. Schnick

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Mayo Clinic

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

50 Participants Needed

Trial Summary

What is the purpose of this trial?

Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models. This study is being done to collect samples of tumor tissues, matched normal tissue when possible, and approximately 50 mL of blood.

Research Team

Aaron S. Mansfield, M.D.

Principal Investigator

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

18 years of age and older

Patient is a good medical candidate for a standard of care or research biopsy or surgical procedure to obtain tissue

Exclusion Criteria

You have a serious heart or lung condition that may put you at risk during the study.

The biopsy procedure is safe and poses no significant risk to the patient.

Have a contraindication to percutaneous biopsy including:

Treatment Details

Interventions

• Tissue Collection

Participant Groups

Group I: Tissue Collection Experimental Treatment 1 Intervention

Research tissue specimen will be obtained during the patient's clinical biopsy or clinical tumor resection, if feasible.

Group II: Buccal Swab Experimental Treatment 1 Intervention

Buccal swab may be requested, if necessary, to generate germline data.

Group III: Blood Collection Experimental Treatment 1 Intervention

Up to 50 mL of research blood will be drawn around the time of the procedure. Additional blood may be collected in selected cases, as warranted, to monitor disease recurrence/remission or perform additional testing

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials

3,427

Recruited

3,221,000+