100 Participants Needed

Ultrasound-Guided Pressure Measurement for Liver Disease

CC
ZH
Overseen ByZaid Haddadin, MS
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Methodist Health System
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The purpose of this study is to evaluate the efficacy, safety, and adequacy of Endoscopic Ultrasound (EUS) Portal Pressure Gradient Measurement (PPGM) in patients undergoing EUS-guided liver biopsies.

Research Team

PK

Prashant Kedia, MD

Principal Investigator

The Methodist Hospital Research Institute

Eligibility Criteria

This trial is for individuals with liver disease who are already scheduled to have an endoscopic ultrasound-guided liver biopsy. Specific eligibility details aren't provided, but typically participants should meet certain health standards and not have conditions that could interfere with the study or their safety.

Inclusion Criteria

I have liver disease or suspected cirrhosis and am considered for a specific medical procedure.
I am referred for an EUS procedure and liver biopsy.

Exclusion Criteria

Patient is pregnant, breast-feeding, or planning to become pregnant during the course of the study
I am unable or unwilling to sign the consent form.
Endoscopic procedures are not safe for me.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Patients undergo Endoscopic-Ultrasound Guided liver biopsies and Portal Pressure Gradient Measurements

2 years

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

  • Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement
Trial Overview The trial is testing a procedure called Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurement (EUS-PPGM) during routine liver biopsies in patients with liver disease to assess its safety and effectiveness.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: TreatmentExperimental Treatment1 Intervention
Patients undergoing Endoscopic-Ultrasound Guided liver biopsies and Endoscopic Ultrasound-Guided Portal Pressure Gradient Measurements

Find a Clinic Near You

Who Is Running the Clinical Trial?

Methodist Health System

Lead Sponsor

Trials
156
Recruited
4,826,000+
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