2400 Participants Needed

Genetic Study for Inflammatory Bowel Disease

(MAAIS Trial)

Recruiting at 10 trial locations
LD
Overseen ByLisa Datta, MS
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Johns Hopkins University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to identify the genes responsible for Inflammatory Bowel Disease (IBD) in African Americans. The research focuses on individuals with or without conditions like Crohn's disease or ulcerative colitis, both types of IBD. Participants will provide health information and a blood sample, which can be collected at a convenient location. The study seeks African Americans with a confirmed IBD diagnosis or without any IBD and no family history of it for comparison. As an unphased study, this research offers participants the chance to contribute to groundbreaking genetic discoveries in IBD.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on collecting health information and a blood sample.

Why are researchers excited about this trial?

The Multi-Center African-American Inflammatory Bowel Disease Study (MAAIS) is not testing a new treatment but is instead focused on understanding how inflammatory bowel disease (IBD) affects African-American individuals differently. Researchers are excited about this trial because it aims to uncover unique genetic, environmental, or lifestyle factors that might contribute to IBD in this population. This could lead to more personalized and effective treatment options in the future, tailored specifically for African-Americans. By identifying these distinctive factors, the study has the potential to improve diagnosis, management, and outcomes for African-American patients with IBD, who are often underrepresented in clinical research.

Who Is on the Research Team?

ML

Mark Lazarev, MD

Principal Investigator

Johns Hopkins University

Are You a Good Fit for This Trial?

Inclusion Criteria

African Americans with a confirmed diagnosis of Inflammatory Bowel Disease (IBD)
African Americans without a diagnosis of IBD and without a family history of IBD for comparison purposes

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Data Collection

Participants provide health information and a blood sample for genetic analysis

1-2 weeks
1 visit (in-person or at a local facility)

Follow-up

Participants' data is analyzed for genetic and environmental factors contributing to IBD

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • N/A

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johns Hopkins University

Lead Sponsor

Trials
2,366
Recruited
15,160,000+

University of Alabama at Birmingham

Collaborator

Trials
1,677
Recruited
2,458,000+

University of Louisville

Collaborator

Trials
353
Recruited
76,400+

University of Maryland, Baltimore

Collaborator

Trials
729
Recruited
540,000+

University of North Carolina, Chapel Hill

Collaborator

Trials
1,588
Recruited
4,364,000+

Meharry Medical College

Collaborator

Trials
19
Recruited
6,000+

Weill Medical College of Cornell University

Collaborator

Trials
1,103
Recruited
1,157,000+

National Institutes of Health (NIH)

Collaborator

Trials
2,896
Recruited
8,053,000+

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator

Trials
2,513
Recruited
4,366,000+

Baylor College of Medicine

Collaborator

Trials
1,044
Recruited
6,031,000+
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