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Behavioural Intervention

Portable Air Cleaners for High Blood Pressure (AirPressureNYC Trial)

N/A

Recruiting

Led By Jonathan Newman

Research Sponsored by NYU Langone Health

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to day 180

Awards & highlights

AirPressureNYC Trial Summary

This trial will assess if using portable air cleaners can reduce PM2.5 air pollution and lower blood pressure, which is a leading global cause of death.

Who is the study for?

This trial is for non-smoking adults with hypertension living in NYC public housing who don't have severe high blood pressure, major arrhythmias, cardiovascular disease, lung disease requiring oxygen, end-stage renal disease or cancer under treatment. They shouldn't plan to travel out of NYC for long periods or change their medication soon.Check my eligibility

What is being tested?

The study tests if portable air cleaners (PACs) can reduce indoor fine particulate matter and lower systolic blood pressure. Participants will be randomly assigned to use either an active PAC that filters the air or a sham PAC that does not work but looks identical.See study design

What are the potential side effects?

Since this trial involves using portable air cleaners rather than medications, there are no direct side effects from drugs. However, participants may experience placebo effects or discomfort due to changes in indoor air quality.

AirPressureNYC Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to day 180

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to day 180

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to day 180 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Average Self-Measured Morning Home Systolic Blood Pressure (AM H-SBP) over 30 Days

Secondary outcome measures

Average Self-Measured Morning Home Systolic Blood Pressure (AM H-SBP) over 180 Days

Average Self-Measured Morning Home Systolic Blood Pressure (AM H-SBP) over 90 Days

AirPressureNYC Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Active Portable Air Cleaner (PAC)Experimental Treatment1 Intervention

Using a double-blind randomized process, active PACs (with HEPA filters inside) will be assembled and placed in the bedroom of study participants. Initiation of the PAC devices will occur at baseline on Day 0. After completion of enrollment, consent and the placement of PACs, electricity monitors, and PurpleAir monitoring, the PAC will be turned on. Participants will be instructed to keep the PACs on in bedrooms during the study duration, closing bedroom doors at night and during the day, when possible. The PAC will run for 24 hours on Day 0 of the study protocol before the 30-day treatment period begins. A kilowatt meter will be installed with the PAC to monitor electricity usage as a measure of adherence.

Group II: Sham PACPlacebo Group1 Intervention

Using a double-blind randomized process, sham PACs (with no filters inside) will be assembled and placed in the bedroom of study participants. Initiation of the PAC devices will occur at baseline on Day 0. After completion of enrollment, consent and the placement of PACs, electricity monitors, and PurpleAir monitoring, the PAC will be turned on. Participants will be instructed to keep PACs on in bedrooms during the study duration, closing bedroom doors at night and during the day, when possible. The PAC will run for 24 hours on Day 0 of the study protocol before the 30-day treatment period begins. A kilowatt meter will be installed with the PAC to monitor electricity usage as a measure of adherence.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

NYU Langone HealthLead Sponsor

1,369 Previous Clinical Trials

840,158 Total Patients Enrolled

National Heart, Lung, and Blood Institute (NHLBI)NIH

3,840 Previous Clinical Trials

47,851,684 Total Patients Enrolled

Jonathan NewmanPrincipal InvestigatorNYU Langone Health

1 Previous Clinical Trials

142 Total Patients Enrolled

Media Library

Active PAC (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05874479 — N/A

High Blood Pressure Research Study Groups: Sham PAC, Active Portable Air Cleaner (PAC)

High Blood Pressure Clinical Trial 2023: Active PAC Highlights & Side Effects. Trial Name: NCT05874479 — N/A

Active PAC (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05874479 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research available to adults aged 18 or older?

"The eligibility criteria for this trial stipulates that all enrollees must be over 18 years old and under 100."

Answered by AI

Who meets the criteria for participating in this clinical research?

"To participate in this trial, individuals should be aged between 18 and 100 years old with hypertension. 440 people need to be enrolled for the experiment to proceed as planned."

Answered by AI

Are there any available slots for participants of this clinical trial?

"Per the information on clinicaltrials.gov, this study has paused recruitment since May 12th 2023 after being initially posted September 1st 23. Despite not accepting new patients right now, there are still 225 other studies that require participants at present."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

2023. "Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05874479.