Sham TMS for Healthy Subjects
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how a person's expectations about treatment can affect mood, motivation, and reactions to daily rewards. Participants will undergo an accelerated sham version of transcranial magnetic stimulation (TMS), meaning no actual brain stimulation will occur. The study examines whether different treatment schedules alter these expectations and their effects. Young English-speaking individuals aged 15-25, without any metal in their bodies that could interfere with MRI scans, may be suitable for this trial. As an unphased trial, it offers participants the chance to contribute to understanding how expectations influence treatment outcomes.
Why are researchers excited about this trial?
While most treatments for neurological conditions rely on active interventions like medication or stimulation, sham Transcranial Magnetic Stimulation (TMS) offers a unique angle by providing no active stimulation at all. Researchers are excited about this trial because it helps distinguish the psychological effects of receiving treatment from the physiological effects of actual TMS. This can deepen our understanding of how expectations and beliefs impact treatment outcomes, potentially leading to more effective and targeted therapies in the future.
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants complete baseline clinical assessments and an MRI session
Treatment
Participants undergo five days of accelerated sham TMS (no active brain stimulation is delivered)
Follow-up
Participants complete post-treatment MRI and follow-up assessments at 1 week and 4 weeks
What Are the Treatments Tested in This Trial?
Interventions
- Transcranial Magnetic Stimulation Sham
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
All study participants will receive sham TMS (no active stimulation will be provided).
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Davis
Lead Sponsor
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