Men-Tailored DPP for Prediabetes
(Power-Up Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to assist men at risk for diabetes by testing a Diabetes Prevention Program (DPP) specifically designed for them, called Men-Tailored DPP (Power-Up). Participants will join either a standard class with mixed-gender sessions or a men-only class, both focusing on food choices, exercise, and stress management over a year. Ideal candidates are men living in the NYC area with a recent diagnosis of prediabetes—a condition where blood sugar levels are higher than normal but not high enough to be diabetes—and a BMI of 25 or higher. As an unphased trial, this study offers participants the chance to contribute to innovative research tailored to their needs.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this Diabetes Prevention Program is safe for men?
Research has shown that the Men-Tailored DPP, also known as Power-Up, helps men manage prediabetes. In one study with 23 men, participants attended about 11 out of 16 sessions. They reported feeling better, eating healthier, exercising more, and improving their overall health, suggesting the program is easy to follow. The studies reported no negative effects, which is encouraging. Since the program involves changes in diet and exercise, it is generally considered safe for participants.12345
Why are researchers excited about this trial?
Researchers are excited about the Men-Tailored DPP (Power-Up) because it offers a fresh approach to managing prediabetes, specifically designed for men. Unlike the standard National Diabetes Prevention Program, which is mixed-gender, this program tailors its classes to address the unique lifestyle and health challenges faced by men. By focusing on personalized discussions around food choices, physical activity, and stress management, Power-Up aims to enhance engagement and effectiveness for male participants, potentially leading to better outcomes in preventing the progression to diabetes.
What evidence suggests that the Men-Tailored DPP could be effective for prediabetes?
Research has shown that a special Diabetes Prevention Program (DPP) for men, called Power-Up, can aid in weight loss and maintaining engagement. Participants in this trial may be randomized to the Power-Up arm, which studies suggest results in greater weight loss at both 16 weeks and 1 year compared to regular programs. The program addresses men's specific needs and challenges in managing diet, exercise, and stress. This personalized approach aims to enhance participation and effectiveness for men at risk of diabetes.23678
Who Is on the Research Team?
Earle Chambers, MD MS
Principal Investigator
Albert Einstein College of Medicine
Are You a Good Fit for This Trial?
This trial is for men who are at least 18 years old with a recent HbA1c level between 5.7%-6.4% or a Diabetes Risk Score of 5 or higher, and a BMI of 25 or more. It's not for those unable to attend group sessions in person, give consent by phone, or complete surveys in English/Spanish.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Core Phase
Participants attend at least 16 classes over the first 6 months focusing on food choices, physical activity, and managing stress
Maintenance Phase
Participants attend 6 additional classes over the next 6 months to maintain lifestyle changes
Follow-up
Participants are monitored for engagement, retention, and weight loss outcomes
What Are the Treatments Tested in This Trial?
Interventions
- Men-Tailored DPP (Power-Up)
Trial Overview
The study tests the effectiveness of a Diabetes Prevention Program specifically designed for men (Power-Up). The program aims to reduce diabetes risk among male participants through tailored interventions.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants randomized to this arm will undergo 16 classes tailored for men, that discuss food choices, physical activity, and managing stress over 6 months, which are called the core, and 6 classes over the following 6 months, which is called the maintenance phase.
Participants randomized to this arm will undergo 16 mixed gender classes that discuss food choices, physical activity, and managing stress over 6 months which are called the core and 6 classes over the following 6 months which is called the maintenance phase.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Albert Einstein College of Medicine
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
New York City Department of Health and Mental Hygiene
Collaborator
Citations
Virtual Diabetes Prevention Program Tailored to Increase ...
Results: We identified 11,052 men for outreach based on EHR data, successfully screened 26% of them, consented and enrolled 22% of these ...
Power-Up: An Effectiveness Trial of the Diabetes Prevention ...
We hypothesize that men randomized to Power-Up will achieve significantly greater weight loss (% weight loss from baseline) at 16-weeks and 1-year than men ...
Engagement in the National Diabetes Prevention Program ...
This qualitative study evaluated reasons for Hispanic men's low engagement in the National Diabetes Prevention Program (NDPP) compared with ...
An Effectiveness Trial of the Diabetes Prevention Program
The hypothesis is that men randomized to Power-Up will achieve significantly greater weight loss (% weight loss from baseline) at 16 weeks and 1 year than men ...
Power-Up: An Effectiveness Trial of the Diabetes ...
The Power-up study was designed to see whether a DPP tailored for men can help improve engagement, participation, and results for men. Participants will be ...
Virtual Diabetes Prevention Program Tailored to Increase ...
The primary aim of the project is to assess the effect of Power-Up versus NDPP on weight loss among men with prediabetes. The secondary aim ...
Power Up for Health: Pilot Study Outcomes of a Diabetes ...
Men (n = 23) attended a mean of 11.6 of 16 sessions. Improvement in depressive symptoms, healthy eating and exercise, and health status were ...
8.
researchgate.net
researchgate.net/publication/323783091_Power_Up_for_Health_Pilot_Study_Outcomes_of_a_Diabetes_Prevention_Program_for_Men_from_Disadvantaged_Neighborhoods(PDF) Power Up for Health : Pilot Study Outcomes of a ...
Men (n = 23) attended a mean of 11.6 of 16 sessions. Improvement in depressive symptoms, healthy eating and exercise, and health status were also seen. While ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.