Electronic Health Record Alerts for Kidney Disease

Overseen By Alexander Chang, MD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Geisinger Clinic

Disqualifiers: Nephrologist appointment, Kidney failure, Palliative care, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of the study is to evaluate prospectively the impact of an electronic health record (EHR) alert on primary care providers' (PCP) referral to Nephrology of Geisinger patients with high risk signs (blood and protein in the urine) of glomerulonephritis. This will help quantify the relative effectiveness of EHR alerts on PCPs' referral patterns.

Are You a Good Fit for This Trial?

Inclusion Criteria

I am 18 years old or older.

* Patients receiving care from any Geisinger primary care provider (record of an encounter with a Geisinger PCP within the last 2 years from date of survey implementation)

* Patients with high-risk glomerulonephritis features i.e. positive test results for hematuria (urine dipstick result with blood 1+ or greater) and proteinuria (2+ or 3+ protein on dipstick or ACR≥300 mg/g or PCR ≥500 mg/g) collected within 12 months of index date.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2 weeks

Intervention

Primary care providers are randomized to receive or not receive an EHR alert during patient visits, prompting referral to Nephrology.

1 month

1 visit (in-person)

Follow-up

Participants are monitored for nephrology referral completion and other exploratory outcomes.

12 months

What Are the Treatments Tested in This Trial?

Interventions

• Electronic Health Record alert

How Is the Trial Designed?

Group I: Patients with PCP receiving EHR Alert Experimental Treatment 1 Intervention

Group II: Patients receiving usual care Active Control 1 Intervention

Patient will receive usual care

Who Is Running the Clinical Trial?

Geisinger Clinic

Lead Sponsor

Trials

159

Recruited

1,976,000+

Novartis

Industry Sponsor

Trials

1,646

Recruited

2,778,000+

Vasant Narasimhan

Novartis

Chief Executive Officer since 2018

MD from Harvard Medical School, Bachelor's in Biological Sciences from University of Chicago, Master's in Public Policy from John F. Kennedy School of Government

Shreeram Aradhye

Novartis

Chief Medical Officer since 2022

MD from Yale University, MSc in Clinical Epidemiology from University of Pennsylvania