Biomarker Analysis for Neuroblastoma
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial focuses on studying biomarkers (biological markers) in tumor tissue samples from patients with newly diagnosed neuroblastoma or ganglioneuroblastoma. Researchers aim to learn more about these biomarkers to better understand and potentially improve cancer treatment. Participants will provide blood, tissue, and bone marrow samples for analysis. Individuals newly diagnosed with neuroblastoma, ganglioneuroblastoma, or certain similar conditions who have not yet started chemotherapy, except in urgent cases, may be eligible. As an unphased trial, this study offers participants the opportunity to contribute to groundbreaking research that could lead to improved cancer treatments.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It mainly focuses on not having received chemotherapy before enrollment, except in certain urgent cases.
Why are researchers excited about this trial?
Researchers are excited about this trial because it focuses on analyzing biomarkers in tumor tissue samples from patients with neuroblastoma or ganglioneuroblastoma. Unlike traditional treatments that primarily target the tumor itself, this approach aims to gather detailed molecular information through advanced techniques like RT-PCR, quantitative PCR, flow cytometry, and FISH. By understanding the specific biomarkers, researchers hope to develop more personalized treatments, potentially leading to better outcomes and fewer side effects for patients. This trial represents a shift towards precision medicine, where treatment decisions are tailored based on the unique characteristics of each patient's cancer.
Who Is on the Research Team?
Michael Hogarty
Principal Investigator
Children's Oncology Group
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Sample Collection and Analysis
Patients undergo collection of blood, tissue, and bone marrow samples for analysis via RT-PCR, quantitative PCR, flow cytometry, and FISH.
Follow-up
Participants are monitored periodically for safety and effectiveness after sample collection and analysis
What Are the Treatments Tested in This Trial?
Interventions
- Cytology Specimen Collection Procedure
- Laboratory Biomarker Analysis
Find a Clinic Near You
Who Is Running the Clinical Trial?
Children's Oncology Group
Lead Sponsor
National Cancer Institute (NCI)
Collaborator