Radiation Therapy for Bone Cancer
(TARGET-RT Trial)
Trial Summary
What is the purpose of this trial?
This study is designed for children, adolescents and young adults undergoing radiation therapy for metastatic sarcoma. The aim of the study is to investigate if the investigators can improve the overall survival of these patients by targeting metastatic sites with radiation.
Research Team
Sahaja Acharya, MD
Principal Investigator
SKCCC Johns Hopkins Medical Institution
Eligibility Criteria
This trial is for children, adolescents, and young adults under 39 with metastatic sarcoma. They must have a performance score of at least 70 or an ECOG status of 0-1, indicating they can carry out daily activities without significant assistance. The cancer must be measurable on scans and may be newly diagnosed or progressive after initial treatment.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Induction Chemotherapy
Participants receive standard of care induction chemotherapy followed by restaging imaging
Consolidative Radiation Therapy (cRT)
Radiation/surgery to the primary site and radiation to all sites of metastatic disease
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Consolidative radiation therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Lead Sponsor
Clark Charitable Foundation
Collaborator