Exercise for Type 2 Diabetes
(GUTFIT Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications. However, you must not have changed your diabetes medications in the last three months to be eligible.
What data supports the effectiveness of the treatment Combined Exercise Intervention for Type 2 Diabetes?
Is exercise safe for people with type 2 diabetes?
Exercise is generally safe for people with type 2 diabetes if certain precautions are taken, such as adapting the exercise to individual health conditions and starting slowly. While there is a risk of minor injuries, like muscle strains, serious adverse events are rare when proper screening and gradual progression are followed.678910
How is the Combined Exercise Intervention treatment unique for managing Type 2 Diabetes?
The Combined Exercise Intervention is unique because it integrates both endurance and resistance exercises tailored to individual needs, focusing on improving metabolic control and muscle strength, especially in patients with different stages of Type 2 diabetes. This personalized approach, often supervised, aims to enhance long-term health benefits and compliance, unlike standard treatments that may not offer such customization.311121314
What is the purpose of this trial?
The goal of this experimental trial is to learn about the changes in bacterial diversity in individuals with type 2 diabetes who perform endurance and strength training at different intensities.Participants with type 2 diabetes will be randomly assigned to 16 weeks of either moderate-intensity endurance and strength training or high-intensity endurance and strength training.Researchers will compare the moderate-intensity and high-intensity exercise groups for differences in glycemia and bacterial diversity.
Research Team
Martin Senechal, Ph.D.
Principal Investigator
University of New Brunswick
Eligibility Criteria
Adults aged 19-64 with type 2 diabetes, not very active (less than 10,000 steps per day), stable on their current diabetes medications for the last three months, and have an HbA1c level of at least 7.5%. They should also be falling short of recommended physical activity levels.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo a supervised exercise intervention of resistance and aerobic training for 16 weeks, performed at either high or moderate intensity
Follow-up
Participants are monitored for changes in glycemic control and gut microbiome diversity after the intervention
Treatment Details
Interventions
- Combined Exercise Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of New Brunswick
Lead Sponsor
Laval University
Collaborator