Light Therapy for Eczema
(BRONTE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing two types of light therapy to find out which is better for treating eczema. It focuses on patients who haven't had success with other treatments. The light therapy helps by reducing skin inflammation and repairing the skin barrier.
Will I have to stop taking my current medications?
You may need to stop certain medications before joining the trial. If you're using phototherapy, oral immune-modulating drugs, or systemic biologics, you must stop them 30 to 90 days before starting. However, topical, intralesional, or inhaled corticosteroids are allowed.
Is light therapy safe for treating eczema?
How is light therapy for eczema different from other treatments?
Light therapy for eczema, specifically using narrowband UVB (NB-UVB), is unique because it uses a specific wavelength of ultraviolet light to reduce inflammation and improve skin conditions. This treatment is particularly effective for moderate to severe cases and is often used when other treatments have not worked well.12367
What data supports the effectiveness of the treatment for eczema?
Who Is on the Research Team?
Aaron M Drucker
Principal Investigator
Women's College Hospital
Are You a Good Fit for This Trial?
This trial is for people with moderate to severe eczema who haven't improved after using topical treatments. They must meet specific criteria for eczema severity and have not used certain medications like systemic biologics, corticosteroids, or immune-modulating agents recently.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either Narrowband or Broadband UVB phototherapy three times weekly
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Broadband UVB phototherapy
- Narrowband UVB phototherapy
Broadband UVB phototherapy is already approved in Canada, United States, European Union for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
Women's College Hospital
Lead Sponsor
University of British Columbia
Collaborator
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborator
University of Toronto
Collaborator