Chiropractic Care for Depression

(DEP Trial)

TP
DS
Overseen ByDaekiara Smith-Ireland, MPH, DrPH
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether chiropractic care can effectively treat adults with mild to moderate depression. Researchers aim to successfully enroll and retain participants while ensuring smooth treatment and study processes. Participants will be divided into two groups: one receiving chiropractic care for six weeks and another on a waitlist, who will receive the treatment later. This trial targets adults experiencing mild to moderate depression symptoms, such as sadness or hopelessness. It excludes individuals with severe depression, untreated mental health issues, or recent chiropractic treatments. As an unphased trial, this study provides a unique opportunity to contribute to understanding new treatment options for depression.

What prior data suggests that chiropractic care is safe for adults with depression?

Studies have shown that chiropractic care is generally safe and well-tolerated. In one study, patients who received chiropractic treatment reported significant improvements in overall quality of life, including better sleep and reduced anxiety. Another report highlighted a woman who experienced fewer anxiety and panic attacks after receiving chiropractic care.

Research also emphasizes a strong focus on patient safety in the chiropractic field, with efforts to prevent harm and improve patient outcomes. While individual experiences can vary, these findings suggest that chiropractic care is a safe option for many people.12345

Why are researchers excited about this trial?

Chiropractic care is unique for depression treatment because it offers a non-pharmacological approach, which might appeal to those seeking alternatives to medications like antidepressants. Unlike standard treatments that often rely on chemical intervention to balance neurotransmitters, chiropractic care focuses on physical adjustments that may influence the nervous system and improve mood. Researchers are excited about this approach because it could provide relief without the side effects commonly associated with traditional depression medications, offering a holistic treatment option that addresses both physical and mental well-being.

What evidence suggests that chiropractic care might be an effective treatment for depression?

Research has shown that chiropractic care might help with depression. In this trial, participants in the intervention group will receive 6 weeks of chiropractic care, while those in the waitlist group will be offered chiropractic care after the initial 6-week assessments. Some studies have found that people receiving chiropractic treatment experienced significant improvements in depression, anxiety, and tiredness. Another study discovered that these treatments could enhance quality of life in just four weeks. Evidence suggests that spinal adjustments might positively impact mental health. While more research is needed, early findings are promising for those considering this approach for depression.13678

Are You a Good Fit for This Trial?

This trial is for adults with mild to moderate depression. Participants must be able to follow pre-treatment instructions, attend all assessments and chiropractic sessions, and complete study activities without excessive burden. Details on specific inclusion or exclusion criteria are not provided.

Inclusion Criteria

Mild to moderate depression (T-score 55-69) as measured by the PROMIS® Depression - Short Form 8a
I am between 18 and 65 years old.

Exclusion Criteria

Severe suicidal risk
Diagnosed with untreated or uncontrolled externalizing disorders or thought disorders
Presence of hearing impairments
See 8 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive 6 weeks of chiropractic care treatment

6 weeks

Waitlist Group Assessment

Participants in the waitlist group undergo 6-week lab assessments before receiving chiropractic care

6 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Chiropractic Care
Trial Overview The study tests the feasibility of a future clinical trial on chiropractic care for depression. It examines participant recruitment, retention, adherence to protocols, completion of assessments and treatments by participants, and strict adherence to adjustments by chiropractors.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Group I: Waitlist Group (WL)Experimental Treatment1 Intervention
Group II: Intervention GroupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Life University

Lead Sponsor

Trials
21
Recruited
450+

Citations

Neurobiological basis of chiropractic manipulative treatment of ...The results confirmed that vertebral manipulative techniques were very effective in improving TTH and depression (33). An interesting case report of a 44 year- ...
Neuroplastic Responses to Chiropractic CareSignificant improvements in light sleep stage were observed in the chiropractic group along with enhanced overall quality of life post 4 weeks, ...
Groundbreaking Study Highlights Mental Health Benefits of ...Enhanced Mental Health. Participants receiving chiropractic care experienced significant improvements in anxiety, depression, and fatigue.
Comparative Effectiveness of Usual Care With or Without ...In this prospective cohort study, the patients referred for chiropractic care showed statistically significant improvement comparable to the propensity score- ...
Study Highlights Mental Health Benefits of Chiropractic1. Enhanced Mental Health – Participants receiving chiropractic care experienced significant improvements in anxiety, depression, and fatigue.
The Effects of Chiropractic on Adults With Depression: a ...Changes from baseline of self-reported outcomes of a comprehensive overview of a patient's physical, mental, and social health utilizing the ...
REDUCED ANXIETY SYMPTOMS IN A PATIENT ...A 38-year-old female presented for chiropractic care with a 3-month history of anxiety and panic attacks, and chronic low back and neck discomfort.
Patient safety culture research within the chiropractic professionA proactive patient safety culture is crucial in healthcare to minimize preventable harm and improve patient outcomes.
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