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Device

Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS) for Cognitive Impairment

N/A
Waitlist Available
Led By Amy Zheng, PhD
Research Sponsored by Casa Colina Hospital and Centers for Healthcare
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Experiencing persistent symptoms of brain fog/cognitive impairment beyond 3 months of COVID-19 infection that are not explained by an alternative diagnosis
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at baseline, at week 3, and at week 7
Awards & highlights

Study Summary

This trial is looking at whether electrical stimulation of a nerve running through the ear could help with long term symptoms of Covid-19, as well as identifying what factors make some people more likely to experience these symptoms.

Eligible Conditions
  • Cognitive Impairment
  • Post-COVID Syndrome

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You have been experiencing ongoing brain fog or cognitive difficulties for more than 3 months after being infected with COVID-19, and doctors cannot find any other explanation for your symptoms.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at baseline, at week 3, and at week 7
This trial's timeline: 3 weeks for screening, Varies for treatment, and at baseline, at week 3, and at week 7 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Dimensional Change Card Sort Test (DCCS) scores
Change in Flanker Inhibitory Control and Attention Test (Flanker) scores
Change in List Sorting Working Memory scores
+2 more
Secondary outcome measures
Change in BURNS Anxiety Inventory scores
Mental Depression
Change in Fatigue Severity Scale scores
+5 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Transcutaneous Vagus Nerve Stimulation (t-VNS)Experimental Treatment1 Intervention
Participants will receive 60 minutes of t-VNS stimulation every day for 10 consecutive days while wearing a fitness tracker.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS)
2022
N/A
~30

Find a Location

Who is running the clinical trial?

Casa Colina Hospital and Centers for HealthcareLead Sponsor
9 Previous Clinical Trials
276 Total Patients Enrolled
Amy Zheng, PhDPrincipal InvestigatorCasa Colina Hospital and Centers for Healthcare
1 Previous Clinical Trials
24 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who is eligible to volunteer for this trial?

"This medical trial is enrolling 20 individuals aged 18-85 with cognitive decline. To be eligible, patients must have been born female and be displaying symptoms of brain fog/cognitive impairment that cannot otherwise be explained for more than 3 months since their COVID-19 diagnosis."

Answered by AI

Is there an age limitation for enrollment in this clinical research endeavor?

"This clinical trial requires participants to be aged between 18 and 85 years old. It is important to note that there are 160 trials specifically for minors, as well as 1423 studies dedicated to seniors."

Answered by AI

What objectives is this experiment aiming to accomplish?

"The principal endpoint of this medical trial, which will be monitored at baseline, week 3 and week 7 is the alteration in Pattern Comparison Processing Speed scores. Secondary endpoints include: changes to PROMIS Sleep Disturbance (which assesses sleep quality), Fatigue Severity Scale (for fatigue) and Sniffin' Sticks olfactory performance (odor threshold)."

Answered by AI

What is the estimated intake of participants in this clinical trial?

"Affirmative, the clinical trial is still in search of participants. According to records on clinicaltrials.gov, this medical study was first announced March 1st 2022 and most recently updated July 20th 2022. The research team aims to recruit a total of twenty individuals from one site."

Answered by AI

Are there any open opportunities for volunteers to join this clinical experiment?

"Clinicaltrials.gov indicates that this research trial is presently recruiting volunteers; the study was first listed on March 1st 2022, and its information was last updated on July 20th 2022."

Answered by AI
~8 spots leftby Mar 2025