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Memory Training for Mild Cognitive Impairment (WMTrain Trial)

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Recruiting

Led By Alexandru Iordan, Ph.D.

Research Sponsored by University of Michigan

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

MCI Diagnosis

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 weeks

Awards & highlights

WMTrain Trial Summary

This trial will test whether working memory training can help people with early memory loss.

Who is the study for?

This trial is for older adults who have been diagnosed with amnestic mild cognitive impairment (MCI). Participants must be able to undergo MRI scans, be right-handed, and not have other neurological conditions, significant mental illnesses, sensory impairments that could affect participation, or a history of substance abuse.Check my eligibility

What is being tested?

The study is testing the effectiveness of working memory training on improving cognitive functions in individuals with MCI. It aims to see if this type of brain exercise can lead to changes in neural activity and enhance memory capabilities.See study design

What are the potential side effects?

Since the intervention involves non-invasive cognitive exercises rather than medication or surgery, no direct physical side effects are expected. However, participants may experience fatigue or frustration during challenging tasks.

WMTrain Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have been diagnosed with mild cognitive impairment.

WMTrain Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in brain activation within the WM network

Gains in WM training task performance

Secondary outcome measures

Changes in criterion (fMRI) WM task performance

Changes in functional connectivity within and between canonical brain networks

WMTrain Trial Design

3Treatment groups

Active Control

Group I: In-Person, MCIActive Control1 Intervention

Participants diagnosed with MCI will undergo 10 sessions of WM training in person.

Group II: Online, HealthyActive Control1 Intervention

Cognitively intact older adults will undergo 10 sessions of WM training online.

Group III: Online, MCIActive Control1 Intervention

Participants diagnosed with MCI will undergo 10 sessions of WM training online.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of MichiganLead Sponsor

1,797 Previous Clinical Trials

6,378,028 Total Patients Enrolled

Alexandru Iordan, Ph.D.Principal InvestigatorUniversity of Michigan

Alexandru IordanPrincipal InvestigatorUniversity of Michigan

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there availability to join this research initiative?

"According to the data available on clinicaltrials.gov, this research project is currently enrolling participants. The trial was first advertised on April 7th 2022 and its details were most recently revised on May 13th 2022."

Answered by AI

What is the current enrollment figure for this research project?

"Affirmative, according to clinicaltrials.gov, this clinical trial is now enlisting participants and was initially posted on April 7th 2022. The most recent update was made on May 13th 2022 and the study requires 30 individuals from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Memory Training and Neural Plasticity

Alexandru Iordan 2022. "Memory Training and Neural Plasticity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05380739.