Prehabilitation for Liver Transplant Candidates
(Prehab preLT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial will test if a program combining exercise, nutrition, and mental health support can help patients with cirrhosis become stronger and healthier before their surgery.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is prehabilitation safe for liver transplant candidates?
How is prehabilitation unique for liver transplant candidates?
Prehabilitation for liver transplant candidates is unique because it focuses on improving physical fitness and overall health before surgery through a structured exercise program, which can enhance recovery and reduce surgical risks. Unlike other treatments that may focus solely on medical management, prehabilitation involves a multidisciplinary approach to optimize the patient's condition before the transplant.12567
What data supports the effectiveness of the treatment Prehabilitation for Liver Transplant Candidates?
Who Is on the Research Team?
Amine Benmassaoud, MD
Principal Investigator
Research Institute of the McGill University Health Centre
Are You a Good Fit for This Trial?
This trial is for adults over 18 who are on the liver transplant waiting list with diagnosed cirrhosis. They must not have severe end-stage liver disease, recent hepatic decompensation, low blood counts, significant heart issues, or conditions that limit movement or cause frequent falls.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Prehabilitation
Participants undergo a multimodal prehabilitation program combining exercise training, nutritional optimization, and psychological support
Follow-up
Participants are monitored for safety and effectiveness after the prehabilitation program
What Are the Treatments Tested in This Trial?
Interventions
- Prehabilitation
Prehabilitation is already approved in European Union, United States, Canada for the following indications:
- Preparation for liver transplantation in patients with cirrhosis
- Preparation for liver transplantation in patients with cirrhosis
- Preparation for liver transplantation in patients with cirrhosis
Find a Clinic Near You
Who Is Running the Clinical Trial?
McGill University Health Centre/Research Institute of the McGill University Health Centre
Lead Sponsor
Canadian Donation and Transplantation Research Program
Collaborator
Canadian Association for the Study of the Liver
Collaborator