Research Procedures for ALS
(CAPTURE-ALS Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The trial aims to learn more about amyotrophic lateral sclerosis (ALS) and related disorders by collecting and studying information from patients' medical records. ALS affects nerve cells in the brain and spinal cord, leading to muscle weakness and movement problems. The trial includes clinical procedures that gather data to help researchers better understand the disease. Suitable candidates include those diagnosed with ALS or a similar disorder, receiving care at a clinic using Epic for electronic health records, and able to give informed consent or have a proxy to do so. As an unphased trial, this study offers a unique opportunity to contribute to the foundational understanding of ALS and related disorders.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
Why are researchers excited about this trial?
Researchers are excited about the clinical procedures being explored for ALS because they aim to uncover novel insights into the disease's progression and response to interventions. Unlike standard treatments that focus on symptom management or slowing disease progression, these procedures could lead to breakthroughs in understanding the underlying mechanisms of ALS. By refining diagnostic techniques or exploring new intervention strategies, this research could pave the way for more effective and targeted therapies in the future.
Who Is on the Research Team?
Michael Benatar, MBChB, MS, DPhil
Principal Investigator
University of Miami
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Data Collection
Systematic gathering of clinical data through the EHR to characterize the natural history of ALS and related diseases
Follow-up
Participants are monitored for safety and effectiveness after data collection
What Are the Treatments Tested in This Trial?
Interventions
- Clinical Procedures
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Miami
Lead Sponsor
National Center for Advancing Translational Science (NCATS)
Collaborator
Muscular Dystrophy Association
Collaborator
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator
National Center for Advancing Translational Sciences (NCATS)
Collaborator
National Institutes of Health (NIH)
Collaborator