Robotic Microsurgery for Alzheimer's Disease

(REMIND Trial)

Recruiting at 1 trial location

Overseen By Clinical Operations

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: MMI (Medical Microinstruments, Inc.)

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

15 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

The objective of this investigational device exemption (IDE) study is to evaluate the safety and feasibility of using the Symani System and microsurgical techniques in the deep cervical lymph node (dCLN) region in the setting of mild to moderate Alzheimer's disease and lymphatic abnormalities.

Are You a Good Fit for This Trial?

Inclusion Criteria

I am 50 years old or older.

Patient has confirmed mild to moderate Alzheimer's Disease according to the National Institute of Aging-Alzheimer's Association (NIA-AA) criteria

Patient has a positive amyloid PET test and/or a positive CSF t-tau/amyloid-beta-42 test

Exclusion Criteria

Patient (or their legally authorized representative) is unwilling to provide informed consent

I have severe kidney disease with very low kidney function.

Clinically significant cardiovascular, digestive, respiratory, endocrine, or central nervous system disorders, previous mental disorders, or other disorders that may significantly affect the data collection or the ability to comply with the protocol per the investigator's discretion

What Are the Treatments Tested in This Trial?

Interventions

• Symani Surgical System

How Is the Trial Designed?

Group I: Alzheimer's Disease Experimental Treatment 1 Intervention

Patient with confirmed mild to moderate Alzheimer's Disease according to the National Institute of Aging-Alzheimer's Association (NIA-AA) criteria

Who Is Running the Clinical Trial?

MMI (Medical Microinstruments, Inc.)

Lead Sponsor