Hookah Smoke Exposure for Secondhand Smoke Effects
Trial Summary
Will I have to stop taking my current medications?
Yes, you must not be on any prescription medications to participate in this trial.
What data supports the effectiveness of the treatment involving charcoal-heated hookah smoke, clean air, and e-hookah aerosol for secondhand smoke effects?
The research indicates that hookah smoke, including charcoal-heated and e-hookah aerosol, contains toxic chemicals that can affect air quality and health, similar to cigarette smoke. However, there is no direct evidence in the provided studies that supports the effectiveness of this treatment for reducing secondhand smoke effects.12345
Is exposure to hookah smoke safe for humans?
Research shows that exposure to hookah smoke, including secondhand smoke, can lead to increased levels of harmful substances like carbon monoxide and particulate matter in the air, which can be unsafe for both adults and children. These substances can affect air quality and pose health risks, suggesting that hookah smoke exposure is not generally considered safe.14567
How does e-hookah aerosol treatment differ from other treatments for secondhand smoke exposure?
E-hookah aerosol treatment is unique because it specifically targets the effects of secondhand smoke from hookahs, which contain toxic chemicals and heavy metals. Unlike traditional cigarette smoke, hookah smoke involves water filtration, but still poses significant health risks, making this treatment novel in addressing these specific exposures.458910
What is the purpose of this trial?
In the United States, secondhand smoke is the third leading preventable cause of death. Flavored hookah (waterpipe) tobacco smoking, a highly social activity common in hookah bars, is a key source of SHS exposure. While smoke-free air laws have decreased exposure to secondhand smoke, the majority of laws do not include hookah smoking. Thus, as a social outlet for youth and young adults, hookah smoke exposure may harm non-smokers, including women of reproductive age or pregnant, hookah bar workers, children, and individuals with heart and lung disease. While more is known on the acute effects of active hookah smoking and the literature is emerging on active e-hookah vaping, little is known about the acute vascular effects of secondhand exposure to hookah smoke and aerosol. The study aims to examine the acute effects of secondhand exposure of hookah smoke and aerosol on endothelial and vascular function. Eligible volunteers will be invited to participate in a total of 3 study visits (2-3 hours each): e-hookah aerosol exposure, charcoal-heated hookah smoke exposure and smoke-free room air. Non-invasive blood pressure and blood flow measurements will be taken before and after the exposure sessions.
Eligibility Criteria
This trial is for non-smokers aged 21-49 with no recent secondhand smoke exposure, not on prescription meds, and without heart or lung disease. Participants must have a resting heart rate below 100 bpm, blood pressure under 140/90 mmHg, and a BMI between 18 and 30. Pregnant or breastfeeding individuals can't join.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Exposure Sessions
Participants undergo three exposure sessions: e-hookah aerosol, charcoal-heated hookah smoke, and clean air, with non-invasive blood pressure and blood flow measurements taken before and after each session.
Follow-up
Participants are monitored for any delayed effects of the exposure sessions.
Treatment Details
Interventions
- Charcoal-heated hookah smoke
- clean air
- e-hookah aerosol
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Los Angeles
Lead Sponsor