Lidocaine Injections for Abdominal Pain

Age: 18+

Sex: Any

Trial Phase: Phase 4

Sponsor: Oregon Health and Science University

Disqualifiers: Visceral pain, Lidocaine allergy, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Prior Safety Data This treatment has passed at least one previous human trial

Compensation: Varies

Number of Visits: 6

Duration: 1 day

45 Participants Needed

Trial Summary

What is the purpose of this trial?

This is a prospective cohort study of outpatient adults with chronic abdominal wall pain receiving abdominal wall injections, as part of their usual care, with lidocaine. Subjects will be recruited at the outpatient gastroenterology clinic at OHSU.

Eligibility Criteria

This trial is for adults with chronic abdominal pain who have a positive Carnett's sign or pain near an incisional site, and suspect their pain is from the abdominal wall. They must be over 18, not pregnant, able to consent, and without severe allergies to lidocaine or bleeding disorders.

Inclusion Criteria

My abdominal pain is thought to come from the abdominal wall.

My average daily pain is 3 or more on a scale of 0 to 10.

I have pain near a surgery scar that worsens when I tense my stomach.

Exclusion Criteria

I have had injections for abdominal pain.

I have a hernia where it hurts in my abdomen.

Unwillingness or inability to provide informed consent

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

1 visit (in-person)

Baseline Assessment

Baseline assessment includes medical history review, survey administration, and Quantitative Sensory Testing

1 week

1 visit (in-person)

Treatment

Participants receive abdominal wall injections with lidocaine

1 day

1 visit (in-person)

Follow-up

Participants are monitored for changes in abdominal wall pain at 1 week, 4 weeks, and 12 weeks following the injection

12 weeks

3 visits (in-person)

Treatment Details

Interventions

• Abdominal wall injections with lidocaine 2%

Trial Overview The study tests if injecting lidocaine into the abdominal wall helps reduce chronic pain in patients. It's conducted at an outpatient clinic where participants receive these injections as part of their usual care.

Participant Groups

Group I: Abdominal wall injections for abdominal wall pain Experimental Treatment 1 Intervention

Patients with abdominal pain who are suspected of having abdominal wall pain.

Who Is Running the Clinical Trial?

Oregon Health and Science University

Lead Sponsor

Trials

1,024

Recruited

7,420,000+