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Triamcinolone Injections for Osteoarthritis

(PRECISION-Knee Trial)

Enrolling by invitation at 3 trial locations
Age: 18+
Sex: Any
Trial Phase: Phase 4
Sponsor: Sosi Dzhugarian
Disqualifiers: Skin infection, Recent fracture, others
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to determine whether a lower dose of corticosteroid injection with ultrasound-guidance for the treatment of knee osteoarthritis can be as effective as a higher dose that is landmark-guided. With landmark-guided dosing, it may be reasonable to use a higher amount of corticosteroid in order to ensure a sufficient amount of the medication is administered, however these injections carry the risk of side effects. Alternatively, with the use of ultrasound, it may be reasonable to use less corticosteroid, possibly decreasing the risk of side effects and increasing patient satisfaction.

Who Is on the Research Team?

GE

Griffin Elbert, DO

Principal Investigator

Community Memorial Healthcare

Are You a Good Fit for This Trial?

Inclusion Criteria

I have symptoms from osteoarthritis in at least one knee.
I can understand and sign consent forms in English or Spanish.
I am 50 years old or older.
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either a 40mg landmark-guided or 20mg ultrasound-guided triamcinolone injection for knee osteoarthritis

Immediate
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

3 months
Multiple visits (in-person and/or virtual)

What Are the Treatments Tested in This Trial?

Interventions

  • Triamcinolone

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: 20mg ultrasound-guided triamcinolone knee injectionExperimental Treatment1 Intervention
Group II: 40mg landmark-guided triamcinolone knee joint injectionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Sosi Dzhugarian

Lead Sponsor

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