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Propranolol for Obstructive Sleep Apnea (ProSAT Trial)
ProSAT Trial Summary
This trial is testing whether a drug called propranolol can help people with obstructive sleep apnea by lowering glucose and free fatty acid levels during sleep, and preserving vascular function.
ProSAT Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowProSAT Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.ProSAT Trial Design
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Who is running the clinical trial?
Media Library
- If you have already taken part in the 'Metabolic Impact of Intermittent CPAP' study, you must have shown a more than 10% increase in nighttime fat or sugar levels during CPAP.I do not have serious heart conditions or uncontrolled high blood pressure.I do not have sleep disorders, diabetes, or severe lung, kidney, or liver issues.I use CPAP regularly but am willing to stop for this study.I have severe obstructive sleep apnea.I am currently taking medication that may interact with the trial drug.
- Group 1: Placebo Oral Tablet
- Group 2: Propranolol Oral Tablet
- Group 3: CPAP
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What are the risks associated with taking Propranolol Oral Tablet?
"Propranolol Oral Tablet, which is currently in Phase 2 trials, received a score of 2. This suggests that while there is some evidence suggesting the medication is safe, there is no data affirming that the drug is effective."
Could I be a candidate for this medication research?
"The target population for this study are those who have obstructive sleep apnea and are aged 20 to 65. Around 36 patients are needed for the trial."
What does Propranolol Oral Tablet help patients with the most?
"Propranolol Oral Tablet is often given to patients in order to lower their risk of cardiovascular mortality. Additionally, this medication can also help treat angina pectoris, myocardial infarction, and obstructive hypertrophic cardiomyopathy."
Is this study still recruiting patients who wish to participate?
"Unfortunately, this clinical trial is no longer looking for new participants. The study was last updated on 8/24/2022 and originally posted on 2/15/2017. However, there are presently 311 trials actively recruiting participants with obstructive sleep apnea (osa) and 43 studies for Propranolol Oral Tablet actively enrolling participants."
Are people of all ages welcome to participate in this research?
"In order to participate in this clinical trial, patients must be 20-65 years old. There are 60 other trials for patients who are younger than 20 and 283 for those who are older than 65."
How many patients are participating in this clinical trial?
"Unfortunately, this particular study is not recruiting at the moment. The clinical trial was initially posted on February 15th, 2017 and last updated on August 24th, 2022. If you are interested in other studies, 311 studies for obstructive sleep apnea (osa) and 43 for Propranolol Oral Tablet are currently enrolling participants."
Who else is applying?
What state do they live in?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
What site did they apply to?
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