Micro-ultrasound vs MRI for Prostate Cancer Screening
(MUSIC-Screen Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to compare whether the FDA and Health Canada approved microUS is as effective as the currently used option (MRI) for imaging the prostate gland. Participants will be randomized into two groups to compare the imaging results of the current standard of care MRI and the new microUS. The study is looking to identify the most effective imaging modality to help guide whether you progress to have a prostate biopsy.
Will I have to stop taking my current medications?
The trial protocol does not specify if you need to stop taking your current medications, but you cannot participate if you've had testosterone replacement or androgen deprivation therapy in the last 12 months.
Is micro-ultrasound safe for prostate cancer screening?
How does the treatment using micro-ultrasound differ from MRI for prostate cancer screening?
Micro-ultrasound is a new imaging technology that uses high-frequency sound waves to create detailed images of the prostate, offering a simpler, more accessible, and potentially less expensive alternative to MRI. Unlike MRI, which requires specialized expertise and equipment, micro-ultrasound can be performed in real-time by urologists, making it a promising tool for detecting and monitoring prostate cancer.678910
What data supports the effectiveness of the treatment ExactVu, MRI, Magnetic Resonance Imaging for prostate cancer screening?
Research shows that high-resolution micro-ultrasound, like ExactVu, can effectively detect prostate cancer by identifying changes in the prostate's structure, similar to MRI. It offers advantages such as being more affordable and easier to access compared to traditional MRI, while still providing reliable detection of significant prostate cancer.57111213
Are You a Good Fit for This Trial?
This trial is for individuals who need screening for prostate cancer. Participants should be eligible and considering a prostate biopsy based on current medical guidelines. The study excludes those with contraindications to MRI, previous reactions to contrast agents used in MRI, or any condition that would interfere with micro-ultrasound imaging.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Imaging
Participants undergo imaging using either microUS or MRI to compare effectiveness in detecting prostate cancer
Follow-up
Participants are monitored for detection of clinically significant prostate cancer
What Are the Treatments Tested in This Trial?
Interventions
- ExactVu
- MRI
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alberta
Lead Sponsor