This trial is testing a donor stem cell transplant with chemotherapy and radiation to see if it can treat blood cancers.
- Mantle Cell Lymphoma
- Diffuse Large B-Cell Lymphoma
- Prolymphocytic Leukaemia
- Large Cell Anaplastic Lymphoma
- Lymphoblastic Lymphoma
- Lymphoplasmacytic Lymphoma
- Refractory Follicular Lymphoma
- Acute Leukemia
- Refractory Marginal Zone Lymphoma
- Small Lymphocytic Lymphoma (SLL)
- Burkitt Lymphoma
- Chronic Myelogenous Leukemia (CML)
- Chronic Lymphocytic Leukemia (CLL)
- Chronic Myeloid Leukemia (CML)
- Chronic Myelomonocytic Leukemia
- Hodgkin's Lymphoma
- Mixed Phenotype Acute Leukemia
- Acute Myeloid Leukemia
- Myelodysplastic Syndrome
- Acute Lymphoblastic Leukemia
1 Primary · 8 Secondary · Reporting Duration: At 1- and 2-years post-transplant
Awards & Highlights
2 Treatment Groups
Arm A (high dose treosulfan)
1 of 2
Arm B (low dose treosulfan)
1 of 2
60 Total Participants · 2 Treatment Groups
Primary Treatment: Allogeneic Hematopoietic Stem Cell Transplantation · No Placebo Group · Phase 2
Who is running the clinical trial?
Age Any Age · All Participants · 1 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
What is the FDA's stance on Allogeneic Hematopoietic Stem Cell Transplantation?
"Allogeneic Hematopoietic Stem Cell Transplantation is still in Phase 2, so there is only preliminary evidence for its safety." - Anonymous Online Contributor
What is the primary reason that Allogeneic Hematopoietic Stem Cell Transplantation is employed?
"Allogeneic Hematopoietic Stem Cell Transplantation is the standard care for transplant patients. Additionally, this intervention can be used to treat disorders like multiple sclerosis and lupus nephritis." - Anonymous Online Contributor
How many people are part of this experiment?
"The clinicaltrials.gov website verifies that this study is seeking patients. This trial was originally posted on January 25th, 2021 and updated as recently as October 26th, 2022. The investigators need to enroll 60 individuals at a single site." - Anonymous Online Contributor
Are there other cases where Allogeneic Hematopoietic Stem Cell Transplantation has been studied?
"A total of 1105 studies are active that involve Allogeneic Hematopoietic Stem Cell Transplantation. Of these, 202 have reached Phase 3 testing. Most of the research taking place for Allogeneic Hematopoietic Stem Cell Transplantation is based in Philadelphia, Pennsylvania; however, there are a total of 31293 locations running trials for this treatment worldwide." - Anonymous Online Contributor
Are patients being recruited for this research project at this time?
"Correct, the listing on clinicaltrials.gov says that this research project is open for recruitment. The study was first announced on January 25th 2021 and updated October 26th 2022. They are looking for 60 individuals total from 1 centre." - Anonymous Online Contributor