This trial studies how well chemotherapy works with surgery and radiation therapy compared to surgery and radiation therapy alone for nasal and paranasal sinus cancer.
- Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma
- Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma
2 Primary · 0 Secondary · Reporting Duration: Up to 5 years
Awards & Highlights
2 Treatment Groups
Arm A (surgery, IMRT, cisplatin, carboplatin)
1 of 2
Arm B (docetaxel, cisplatin, carboplatin, surgery, IMRT)
1 of 2
82 Total Participants · 2 Treatment Groups
Primary Treatment: Image Guided Radiation Therapy · No Placebo Group · Phase 2
Who is running the clinical trial?
Age 18+ · All Participants · 3 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
- Adilbay, Dauren, Cristina Valero, Conall Fitzgerald, Avery Yuan, Ximena Mimica, Piyush Gupta, Richard J. Wong, et al.. 2022. “Outcomes in Surgical Management of Sinonasal Malignancy—a Single Comprehensive Cancer Center Experience”. Head & Neck. Wiley. doi:10.1002/hed.26989.
- 2018. "Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03493425.
Frequently Asked Questions
What ailment or medical issue does Therapeutic Conventional Surgery commonly address?
"Therapeutic Conventional Surgery is an effective means of treating melanoma, head cancer and soft tissue sarcoma." - Anonymous Online Contributor
Does this experiment have any available slots for participants?
"This clinical trial, which was brought to light on March 28th 2018, is currently seeking patients. The entry has been updated as recently as December 16th 2021 according to the documents on clinicaltrials.gov" - Anonymous Online Contributor
Has the FDA sanctioned Therapeutic Conventional Surgery?
"With some evidence to back up its safety, our team at Power assigned Therapeutic Conventional Surgery a rating of 2 on the 1-3 scale. As this is only Phase 2 trial, there are no findings yet that demonstrate efficacy." - Anonymous Online Contributor
Are there any other scholarly examinations that have looked into the effectiveness of Therapeutic Conventional Surgery?
"Presently, there are 1,398 active studies on Therapeutic Conventional Surgery with 473 of them in the third stage. While most of such trials take place at Shanghai medical centres, 81295 sites globally offer treatments related to this surgery." - Anonymous Online Contributor
How many healthcare settings are currently administering this experiment?
"This clinical trial is recruiting participants from numerous medical faculties, including Mount Sinai Hospital in Detroit, Michigan, Wayne State University/Karmanos Cancer Institute in Bronx, Montana and Montefiore Medical Center - Moses Campus in Great Falls, Wisconsin." - Anonymous Online Contributor
What is the upper limit of individuals participating in this research endeavor?
"Indeed, the information available on clinicaltrials.gov indicates that this medical trial is presently recruiting participants. It was initially posted on March 28th 2018 and recently updated on December 16th 2021. 82 individuals from 100 sites are required for successful completion of the study." - Anonymous Online Contributor