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Ketamine for Treatment-Resistant Depression
Study Summary
This trial is testing whether the antidepressant effects of ketamine are greater in people with a family history of alcohol use disorder, who may respond differently to both alcohol and ketamine.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Find a Location
Who is running the clinical trial?
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- I have a history of or currently have a severe mental health condition like schizophrenia or bipolar disorder.I've had seizures of unknown cause or a serious head injury.I haven't had ECT, TMS, or VNS for depression in the last 4 weeks.I am not taking any medications that are not allowed in the study.I am currently in therapy like CBT or IPT for mood or anxiety.I don't know my family's mental and substance use history.I do not have any serious, unstable health conditions.I have a condition like high blood pressure or diabetes that could affect my brain.I have not taken fluoxetine in the last 5 weeks.I have tried at least one antidepressant that didn't work for me.Your score on a depression test called MADRS is 20 or higher before and on the day of the ketamine treatment.You have received deep brain stimulation treatment in the past.I am between 21 and 65 years old.I have been on psychiatric medication for at least two weeks.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Has this remedy been approved by the federal government?
"The safety of this treatment was adjudicated to be a 2, as Phase 2 trials suggest the presence of some clinical data supporting its security but no evidence yet for effectiveness."
Are there any specific criteria which make someone eligible to enroll in this experiment?
"Eligibility for this clinical trial requires that participants have a diagnosis of alcoholism, and are between 21 and 65 years old. In total, 60 individuals will be admitted to the study."
To what extent is enrollment to this medical experiment open?
"Affirmative. According to clinicaltrials.gov, this medical investigation initiated on April 23rd 2014 and recently updated on August 25th 2022 is actively recruiting patients from a single location with the aim of finding 60 participants in total."
Is this research endeavor currently in need of participants?
"The medical study, which was originally made available on April 23rd 2014 has been recently updated as of August 25th 2022 and is now actively enrolling participants."
Does the age requirement for enrollment in this trial extend beyond 70 years?
"This medical trial has specified that suitable candidates must be between 21 and 65 years of age. Alternatively, there are 217 trials designed specifically for minors while 1187 studies have been developed to serve patients older than 65."
Who else is applying?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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