150 Participants NeededMy employer runs this trial
Veverimer for Metabolic Acidosis
Recruiting at 15 trial locations
AR
Overseen ByAyla Rasmussen
Age: 18+
Sex: Any
Trial Phase: Phase 3
Sponsor: Renibus Therapeutics, Inc.
Pivotal Trial (Near Approval)This treatment is in the last trial phase before FDA approval
Prior Safety DataThis treatment has passed at least one previous human trial
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this 26 week study is is to evaluate the efficacy and safety of veverimer in treating adults with moderate-to-severe chronic kidney disease (CKD) and metabolic acidosis.
Are You a Good Fit for This Trial?
Inclusion Criteria
Women of childbearing potential: negative pregnancy test and agree to abstinence or contraception
During screening: 2 central SBC values 12-21 mmol/L
Willing to maintain stable diet
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Exclusion Criteria
I am not able to safely do physical performance tests or my STS5 time is under 10 seconds.
I have had gastroparesis or bariatric surgery.
Participant deemed inappropriate for CPET
See 20 more
What Are the Treatments Tested in This Trial?
Interventions
- Veverimer
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Group I: VeverimerExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
Renibus Therapeutics, Inc.
Lead Sponsor
Trials
8
Recruited
1,200+
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