~28 spots leftby Apr 2026

PRISM for Cancer

(PRISM-AC Trial)

Recruiting at 6 trial locations
AR
Overseen byAbby R Rosenberg, MD, MS, MA
Age: < 65
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Dana-Farber Cancer Institute
No Placebo Group
Approved in 1 Jurisdiction

Trial Summary

What is the purpose of this trial?

Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer

Research Team

AR

Abby R Rosenberg, MD, MS, MA

Principal Investigator

Dana-Farber Cancer Institute

Eligibility Criteria

This trial is for adolescents and young adults aged 12-24 with advanced cancer, who can speak and read English or Spanish. They should be cognitively able to participate in interviews. It's not open to those whose parents refuse participation (if under 18) or if the patient themselves refuses.

Inclusion Criteria

I am between 12 and 24 years old.
My advanced cancer is getting worse or not responding to treatment.
I am mentally capable of participating in interviews.
See 2 more

Exclusion Criteria

I have chosen not to participate in certain treatments.
My parents have not refused participation in the trial.

Treatment Details

Interventions

  • Promoting Resilience in Stress Management (PRISM) (Behavioral Intervention)
Trial OverviewThe PRISM intervention is being tested in this study across multiple sites. The goal of PRISM is to help these young individuals manage stress, improve resilience, and enhance their quality of life while dealing with advanced cancer.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Promoting Resilience in Stress Management (PRISM)Experimental Treatment1 Intervention
Resilience Skills Training
Group II: Usual CareActive Control1 Intervention
Standard psychosocial care

Find a Clinic Near You

Who Is Running the Clinical Trial?

Dana-Farber Cancer Institute

Lead Sponsor

Trials
1,128
Recruited
382,000+

Pittsburgh Children's Hospital

Collaborator

Trials
1
Recruited
200+

Children's Hospital Los Angeles

Collaborator

Trials
257
Recruited
5,075,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

University of Pittsburgh Medical Center

Collaborator

Trials
78
Recruited
77,600+

Seattle Children's Hospital

Collaborator

Trials
319
Recruited
5,232,000+

Baylor College of Medicine

Collaborator

Trials
1,044
Recruited
6,031,000+