Promoting Resilience in Stress Management (PRISM) for Depression

Phase-Based Progress Estimates
Depression+6 MorePromoting Resilience in Stress Management (PRISM) - Behavioral
12 - 24
All Sexes
What conditions do you have?

Study Summary

This trial is testing whether the PRISM intervention can help adolescents and young adults with advanced cancer manage stress.

Eligible Conditions
  • Depression
  • Cancer
  • Communication
  • Coping Skills
  • Hope
  • Quality of Life
  • Anxiety

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

1 Primary · 8 Secondary · Reporting Duration: 3-months

Connor Davidson Resilience Scale
Hope scale score
Hospital Anxiety and Depression Scale (HADS) score
Memorial Symptom Assessment Scale score
Parent Anxiety (Generalized Anxiety Disorder, GAD-7, scores)
Mental Depression
Parent Health-Related Quality of Life (SF-36 scores)
PedsQL Generic Core and Cancer-Specific Quality of Life scores
Palliative Care Engagement

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Usual Care
1 of 2
Promoting Resilience in Stress Management (PRISM)
1 of 2

Active Control

Experimental Treatment

195 Total Participants · 2 Treatment Groups

Primary Treatment: Promoting Resilience in Stress Management (PRISM) · No Placebo Group · Phase 3

Promoting Resilience in Stress Management (PRISM)
Experimental Group · 1 Intervention: Promoting Resilience in Stress Management (PRISM) · Intervention Types: Behavioral
Usual CareNoIntervention Group · 1 Intervention: Usual Care · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3-months

Who is running the clinical trial?

Pittsburgh Children's HospitalUNKNOWN
University of Pittsburgh Medical CenterOTHER
56 Previous Clinical Trials
73,003 Total Patients Enrolled
1 Trials studying Depression
75 Patients Enrolled for Depression
Seattle Children's HospitalLead Sponsor
262 Previous Clinical Trials
5,185,355 Total Patients Enrolled
7 Trials studying Depression
655 Patients Enrolled for Depression
Baylor College of MedicineOTHER
919 Previous Clinical Trials
5,986,223 Total Patients Enrolled
21 Trials studying Depression
2,710 Patients Enrolled for Depression
Dana-Farber Cancer InstituteOTHER
1,016 Previous Clinical Trials
393,621 Total Patients Enrolled
Children's Hospital Los AngelesOTHER
205 Previous Clinical Trials
5,071,982 Total Patients Enrolled
3 Trials studying Depression
134 Patients Enrolled for Depression
Abby R Rosenberg, MD, MS, MAPrincipal InvestigatorDana-Farber Cancer Institute
1 Previous Clinical Trials
74 Total Patients Enrolled
1 Trials studying Depression
74 Patients Enrolled for Depression

Eligibility Criteria

Age 12 - 24 · All Participants · 5 Total Inclusion Criteria

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Who else is applying?

What state do they live in?
How old are they?
18 - 65100.0%
What site did they apply to?
Children's Hospital Los Angeles50.0%
Texas Children's Hospital50.0%
What portion of applicants met pre-screening criteria?
Met criteria66.7%
Did not meet criteria33.3%