Promoting Resilience in Stress Management (PRISM) for Depression

Phase-Based Progress Estimates
2
Effectiveness
3
Safety
Depression+6 MorePromoting Resilience in Stress Management (PRISM) - Behavioral
Eligibility
12 - 24
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether the PRISM intervention can help adolescents and young adults with advanced cancer manage stress.

Eligible Conditions
  • Depression
  • Cancer
  • Communication
  • Coping Skills
  • Hope
  • Quality of Life
  • Anxiety

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

1 Primary · 8 Secondary · Reporting Duration: 3-months

3-months
Connor Davidson Resilience Scale
Hope scale score
Hospital Anxiety and Depression Scale (HADS) score
Memorial Symptom Assessment Scale score
Parent Anxiety (Generalized Anxiety Disorder, GAD-7, scores)
Mental Depression
Parent Health-Related Quality of Life (SF-36 scores)
PedsQL Generic Core and Cancer-Specific Quality of Life scores
3-months.
Palliative Care Engagement

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Usual Care
1 of 2
Promoting Resilience in Stress Management (PRISM)
1 of 2

Active Control

Experimental Treatment

195 Total Participants · 2 Treatment Groups

Primary Treatment: Promoting Resilience in Stress Management (PRISM) · No Placebo Group · Phase 3

Promoting Resilience in Stress Management (PRISM)
Behavioral
Experimental Group · 1 Intervention: Promoting Resilience in Stress Management (PRISM) · Intervention Types: Behavioral
Usual CareNoIntervention Group · 1 Intervention: Usual Care · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3-months

Who is running the clinical trial?

Pittsburgh Children's HospitalUNKNOWN
University of Pittsburgh Medical CenterOTHER
56 Previous Clinical Trials
73,003 Total Patients Enrolled
1 Trials studying Depression
75 Patients Enrolled for Depression
Seattle Children's HospitalLead Sponsor
262 Previous Clinical Trials
5,185,355 Total Patients Enrolled
7 Trials studying Depression
655 Patients Enrolled for Depression
Baylor College of MedicineOTHER
919 Previous Clinical Trials
5,986,223 Total Patients Enrolled
21 Trials studying Depression
2,710 Patients Enrolled for Depression
Dana-Farber Cancer InstituteOTHER
1,016 Previous Clinical Trials
393,621 Total Patients Enrolled
Children's Hospital Los AngelesOTHER
205 Previous Clinical Trials
5,071,982 Total Patients Enrolled
3 Trials studying Depression
134 Patients Enrolled for Depression
Abby R Rosenberg, MD, MS, MAPrincipal InvestigatorDana-Farber Cancer Institute
1 Previous Clinical Trials
74 Total Patients Enrolled
1 Trials studying Depression
74 Patients Enrolled for Depression

Eligibility Criteria

Age 12 - 24 · All Participants · 5 Total Inclusion Criteria

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Who else is applying?

What state do they live in?
Texas66.7%
California33.3%
How old are they?
18 - 65100.0%
What site did they apply to?
Children's Hospital Los Angeles50.0%
Texas Children's Hospital50.0%
What portion of applicants met pre-screening criteria?
Met criteria66.7%
Did not meet criteria33.3%