FDG PET/MRI for Hip Impingement

Age: 18 - 65
Sex: Any
Trial Phase: Phase 2
Sponsor: University of Wisconsin, Madison
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to identify differences in hip scans among individuals who require a second hip surgery, those whose hip pain resolves after the first surgery, and those opting for steroid injections for pain. The focus is on using FDG PET/MRI, an advanced imaging technique, to examine the hips. Individuals who have undergone hip surgery on one side, continue to experience significant pain six months later, and have not had major complications or health-affecting conditions may be suitable candidates. This study seeks to improve understanding and treatment of hip pain. As a Phase 2 trial, the research measures the treatment's effectiveness in an initial, smaller group, allowing participants to contribute to advancements in hip pain management.

Will I have to stop taking my current medications?

The trial information does not specify if you need to stop taking your current medications. It might be best to discuss this with the trial coordinators or your doctor.

What prior data suggests that FDG PET/MRI is safe for hip impingement?

Research shows that FDG PET/MRI is being explored for imaging hip issues, such as femoroacetabular impingement (FAI). This method combines PET, which reveals how body tissues function, with MRI, which provides detailed images of organs and structures.

FDG PET/MRI is generally well-tolerated and is already used in some medical settings for conditions like chronic low back or hip pain. Although specific side effects in hip impingement cases are not well-documented, its use in standard care for other conditions suggests it is relatively safe. The ongoing study aims to confirm this.12345

Why are researchers excited about this trial?

Researchers are excited about FDG PET/MRI for hip impingement because it offers a unique way to visualize and assess the condition. Unlike standard imaging techniques like X-rays or traditional MRIs, FDG PET/MRI combines metabolic and anatomical imaging, providing a more comprehensive view of the hip joint. This means doctors can better understand the extent of inflammation and tissue changes, potentially leading to more targeted and effective treatments. This approach could improve outcomes for patients undergoing revision hip arthroscopy by tailoring interventions based on detailed imaging insights.

What evidence suggests that FDG PET/MRI is effective for hip impingement?

Studies have shown that FDG PET/MRI is promising for detecting issues in the hip area, such as tendonitis. This imaging method combines PET, which reveals tissue activity, with MRI, which offers detailed structural images. Research suggests it can effectively identify hip issues that standard tests might miss. In this trial, participants who have undergone revision hip arthroscopy will receive an FDG PET/MRI. This approach could help doctors gain a clearer understanding of the hip's condition and assist in making treatment decisions by showing the hip's appearance after various treatments.12567

Who Is on the Research Team?

AS

Andrea Spiker, MD

Principal Investigator

University of Wisconsin, Madison

Are You a Good Fit for This Trial?

This trial is for individuals with hip impingement who have undergone a first hip arthroscopy but still experience pain, and those considering steroid injections for pain management. Specific eligibility criteria are not provided.

Inclusion Criteria

Does not have evidence of depression or other major mental health conditions before the index hip arthroscopy
Not currently pregnant
I am between 18 and 45 years old.
See 6 more

Exclusion Criteria

I was diagnosed with depression or another major mental health condition before my hip surgery.
I need opioids for ongoing pain or have a history of opioid misuse.
Currently pregnant
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Imaging

Participants will complete one FDG PET/MRI scan to identify lesions in the hip

1 day
1 visit (in-person)

Follow-up

Participants are monitored for changes in lesions and pain symptoms over time

12 months

What Are the Treatments Tested in This Trial?

Interventions

  • FDG PET/MRI
Trial Overview The study aims to compare the hips of patients after revision hip arthroscopy with those whose pain was resolved by initial surgery or managed by steroid injections, using one FDG PET/MRI scan.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Revision hip arthroscopyExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Wisconsin, Madison

Lead Sponsor

Trials
1,249
Recruited
3,255,000+

Arthroscopy Association of North America

Collaborator

Trials
4
Recruited
650+

Citations

Effectiveness of 18F-fluoro-deoxyglucose Positron ...The result of the current case study suggest 18F-FDG-PET/CT or 18F-FDG-PET/MRI will be useful to detect iliopsoas tendonitis within metal ...
An Updated Review of Femoroacetabular Impingement ...MRI can be used to further delineate labral and chondral injuries, while also ruling out other causes of hip pain.
The effectiveness of adding 18F-FDG PET/MRI to standard ...This project aims to study the effectiveness of adding 18F-FDG PET/MRI to standard clinical care in patients with chronic low back or hip ...
Imaging of femoroacetabular impingement-current conceptsHowever, superior results were noted for the detection of acetabular cartilage lesions using MRA (sensitivity, 71–81%) compared with MRI (sensitivity, 58–65%; [ ...
A meta-analysis of the effectiveness and side effects of hip ...The purpose of this meta-analysis is to assess the effectiveness and safety of hip arthroscopy compared to open surgical dislocation for the treatment of ...
acr–spr–ssr practice parameter for the performance and ...This document is an educational tool designed to assist practitioners in providing appropriate radiologic care for patients.
Recognition of the Femoroacetabular Impingement ...FAI is increasingly recognized as a cause of undiagnosed hip pain in young adults. ... It has been shown to be associated with labral tears, chondral damage, and ...
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