Ondansetron + Lidocaine for Injection Site Reaction
What You Need to Know Before You Apply
What is the purpose of this trial?
This study is a randomized, single-site clinical trial that will take place at Children's Healthcare of Atlanta at Egleston. The investigators want to see if in pediatric patients, giving Zofran prior to propofol, reduces the pain that patients often experience when propofol is injected through an IV. Subjects will be randomized to 1 of 2 groups: lidocaine (common standard of care), or Zofran. The investigators hope to show a means of improving pain control in their patients undergoing anesthesia.
Who Is on the Research Team?
Vipin Bansal, MD
Principal Investigator
Emory University
Are You a Good Fit for This Trial?
This trial is for children aged 2-17 undergoing surgery at Children's Healthcare of Atlanta Egleston, with a working IV in their arm and an ASA score of 1-3. They must not have chronic pain syndromes, long QT syndrome, weigh over 40kg, allergies to the study meds, or have taken opioids within 30 minutes before anesthesia.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either ondansetron or lidocaine prior to propofol injection during surgery
Follow-up
Participants are monitored for pain and vital signs during and immediately after propofol injection
What Are the Treatments Tested in This Trial?
Interventions
- Lidocaine
- Ondansetron
Lidocaine is already approved in United States, European Union, Canada for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
Emory University
Lead Sponsor