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Xylitol Wipes for Bloodstream Infections in Stem Cell Transplant Patients
Study Summary
This trial will evaluate if twice daily wipes with xylitol can reduce bloodstream infections in kids getting stem cell transplants, helping to prevent morbidity and mortality.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I had radiation for cancer in my mouth, head, or neck within the last 6 months.I am scheduled for a stem cell transplant at a specified hospital.I agree not to use xylitol-containing gum or toothpaste during the study.I am receiving extra radiation to my head as part of my total body treatment.I am having a stem cell transplant without prior chemotherapy or radiation.I am willing and able to follow all study rules and attend all appointments.I am between 4 months and 25 years old.I have at least one tooth.
- Group 1: Grape-flavored Wipes
- Group 2: Xylitol
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the enrollment criteria for this trial inclusive of individuals aged 35 and above?
"This study requests participants between the ages of 4 Months and 25 years old. Specifically, 226 trials are available for persons younger than 18 while 728 studies target those over 65."
Who is able to access the opportunity of becoming a participant in this research?
"This clinical experiment requires 419 subjects aged 4 to 25 months that are willing and able to complete the necessary procedures, have undergone a stem cell transplant at one of 3 specified hospitals, possess at least one tooth, and abstain from any xylitol-containing gum or toothpaste during their participation. Moreover, all participants must sign an informed consent form."
How potentially hazardous is Xylitol for people receiving treatment?
"Despite Xylitol receiving a score of 2, there is still limited data regarding its efficacy. To date, however, the compound has demonstrated some measure of safety in accordance with Phase 2 trial guidelines."
Are there any opportunities to join this research project at the moment?
"According to the clinicaltrials.gov database, this experiment is not currently recruiting any new participants; it was first posted on November 1st 2022 and last edited on October 11th of that same year. However, many other trials are still actively seeking volunteers at this time with 911 options listed in total."
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