Study Summary
This trial will evaluate if twice daily wipes with xylitol can reduce bloodstream infections in kids getting stem cell transplants, helping to prevent morbidity and mortality.
- Allogeneic Stem Cell Transplant
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 6 Secondary · Reporting Duration: 33 days
Trial Safety
Phase-Based Safety
Trial Design
2 Treatment Groups
Xylitol
1 of 2
Grape-flavored Wipes
1 of 2
Experimental Treatment
Non-Treatment Group
419 Total Participants · 2 Treatment Groups
Primary Treatment: Xylitol · Has Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 4 - 25 · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Is the enrollment criteria for this trial inclusive of individuals aged 35 and above?
"This study requests participants between the ages of 4 Months and 25 years old. Specifically, 226 trials are available for persons younger than 18 while 728 studies target those over 65." - Anonymous Online Contributor
Who is able to access the opportunity of becoming a participant in this research?
"This clinical experiment requires 419 subjects aged 4 to 25 months that are willing and able to complete the necessary procedures, have undergone a stem cell transplant at one of 3 specified hospitals, possess at least one tooth, and abstain from any xylitol-containing gum or toothpaste during their participation. Moreover, all participants must sign an informed consent form." - Anonymous Online Contributor
How potentially hazardous is Xylitol for people receiving treatment?
"Despite Xylitol receiving a score of 2, there is still limited data regarding its efficacy. To date, however, the compound has demonstrated some measure of safety in accordance with Phase 2 trial guidelines." - Anonymous Online Contributor
Are there any opportunities to join this research project at the moment?
"According to the clinicaltrials.gov database, this experiment is not currently recruiting any new participants; it was first posted on November 1st 2022 and last edited on October 11th of that same year. However, many other trials are still actively seeking volunteers at this time with 911 options listed in total." - Anonymous Online Contributor