21 Participants NeededMy employer runs this trial

hNSC-01 for Huntington's Disease

(REGEN4HD Trial)

UA
Overseen ByUCI Alpha Clinic
Age: 18+
Sex: Any
Trial Phase: Phase 1 & 2
Sponsor: Leslie Thompson
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.

Are You a Good Fit for This Trial?

Inclusion Criteria

I am able to make my own decisions and sign consent forms.
Please note this may not be a complete list of eligibility criteria.
I am between 18 and 65 years old.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive implantation of hNSC-01 to assess safety and tolerability

12 weeks
Multiple visits for surgery and monitoring

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 months
Regular visits for assessments and monitoring

Long-term follow-up

Longer term safety assessment including adverse events and various clinical evaluations

12 months

What Are the Treatments Tested in This Trial?

Interventions

  • hNSC-01

How Is the Trial Designed?

4

Treatment groups

Active Control

Group I: Cohort AActive Control1 Intervention
Group II: Cohort BActive Control1 Intervention
Group III: Cohort CActive Control1 Intervention
Group IV: Cohort DActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Leslie Thompson

Lead Sponsor

California Institute for Regenerative Medicine (CIRM)

Collaborator

Trials
70
Recruited
3,300+

University of California, Irvine

Collaborator

Trials
580
Recruited
4,943,000+