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PET Imaging Agent

Brain Imaging for Cannabis Use Effects in Older Adults

Phase 1 & 2
Recruiting
Led By Rajiv Radhakrishnan, MBBS, MD
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 month
Awards & highlights

Study Summary

This trial will study the effects of cannabis use on the brain of older adults.

Who is the study for?
This trial is for men and women over the age of 50 who can consent to participate. They must not have significant medical or neurological diseases, and women able to bear children should agree to use birth control during the study. People cannot join if they've recently donated blood, are pregnant or lactating, have been exposed to a lot of radiation, or have bleeding disorders.Check my eligibility
What is being tested?
The study is looking at how cannabis affects brain connections in older adults by using a special PET scan called [11C]UCB-J PET imaging. It aims to understand changes in synaptic density related to cannabis use.See study design
What are the potential side effects?
[11C]UCB-J PET imaging involves exposure to a small amount of ionizing radiation which carries a risk similar to that of conventional medical imaging procedures.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 month
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Hippocampal synaptic density

Trial Design

2Treatment groups
Experimental Treatment
Group I: Healthy controlsExperimental Treatment1 Intervention
Subjects undergo a single PET scan using [11C]UCB-J
Group II: Cannabis using older adultsExperimental Treatment1 Intervention
Subjects undergo a single PET scan using [11C]UCB-J

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Yale UniversityLead Sponsor
1,848 Previous Clinical Trials
2,737,794 Total Patients Enrolled
3 Trials studying Cannabis Use
90 Patients Enrolled for Cannabis Use
National Institute on Drug Abuse (NIDA)NIH
2,468 Previous Clinical Trials
2,619,324 Total Patients Enrolled
28 Trials studying Cannabis Use
6,133 Patients Enrolled for Cannabis Use
Rajiv Radhakrishnan, MBBS, MDPrincipal InvestigatorYale University

Media Library

[11C]UCB-J PET (PET Imaging Agent) Clinical Trial Eligibility Overview. Trial Name: NCT05465538 — Phase 1 & 2
Cannabis Use Research Study Groups: Healthy controls, Cannabis using older adults
Cannabis Use Clinical Trial 2023: [11C]UCB-J PET Highlights & Side Effects. Trial Name: NCT05465538 — Phase 1 & 2
[11C]UCB-J PET (PET Imaging Agent) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05465538 — Phase 1 & 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any current openings for this clinical trial?

"This trial, which is seeking participants, was first posted on July 6th, 2022 and was last updated on August 17th, 2022."

Answered by AI

How many subjects are a part of this investigation?

"That is correct. According to clinicaltrials.gov, this study is still recruiting participants. The trial was announced on 7/6/2022 and edited for the last time on 8/17/2022. They are looking for 24 patients from a single location."

Answered by AI

Who else is applying?

What state do they live in?
Connecticut
How old are they?
18 - 65
What site did they apply to?
Connecticut Mental Health Center
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
SV2A in Older Adults
Rajiv Radhakrishnan, MD 2022. "SV2A in Older Adults". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05465538.
~5 spots leftby Sep 2024
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