OP-1250 for Breast Cancer

Phase-Based Progress Estimates
OHSU Knight Cancer Institute, Portland, ORBreast Cancer+1 MoreOP-1250 - Drug
All Sexes
What conditions do you have?

Study Summary

This trial is testing a new drug, OP-1250, to see if it is safe and effective against tumors.

Eligible Conditions
  • Hormone Receptor-positive Breast Cancer
  • HER2-negative Breast Cancer

Treatment Effectiveness

Effectiveness Progress

1 of 3

Similar Trials

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Up to one year

Up to one year
Determine MTD and/or RP2D of OP-1250 when used as a single agent

Trial Safety

Safety Progress

1 of 3

Similar Trials

Trial Design

2 Treatment Groups

OP-1250 Expansion
1 of 2
OP-1250 Dose Escalation
1 of 2

Experimental Treatment

94 Total Participants · 2 Treatment Groups

Primary Treatment: OP-1250 · No Placebo Group · Phase 1 & 2

OP-1250 Expansion
Experimental Group · 1 Intervention: OP-1250 · Intervention Types: Drug
OP-1250 Dose Escalation
Experimental Group · 1 Intervention: OP-1250 · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: up to one year

Who is running the clinical trial?

Olema Pharmaceuticals, Inc.Lead Sponsor
2 Previous Clinical Trials
90 Total Patients Enrolled
1 Trials studying Breast Cancer
30 Patients Enrolled for Breast Cancer
Jo Anne Zujewski, MDStudy DirectorOlema Pharmaceuticals, Inc.
Trinh LeStudy DirectorOlema Pharmaceuticals, Inc.
1 Previous Clinical Trials
11 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

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Frequently Asked Questions

In how many different areas is this trial accessible?

"There are 4 sites running this trial at the moment, located in Sarasota, Orlando, Nashville and other locations. If you wish to participate it would be best to select a location nearest to you so as to not incur extensive travel costs." - Anonymous Online Contributor

Unverified Answer

Are recruitment efforts for this trial still underway?

"That is correct. The clinical trial, which began recruiting on August 13th 2020, is currently looking for 94 patients at 4 different hospitals or medical centres." - Anonymous Online Contributor

Unverified Answer

How many participants are currently enrolled in this trial?

"The sponsor, Olema Pharmaceuticals, Inc., needs 94 eligible patients to proceed with the trial. The research will be conducted in Advent Health (Orlando, Tennessee) and Florida Cancer Center (Sarasota, Florida)." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.