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Cancer Imaging Agent

18FCH PET/CT for Parathyroid Adenomas (18FCH Trial)

Phase 2 & 3

Recruiting

Research Sponsored by Andrei Iagaru

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 1 hour

Awards & highlights

18FCH Trial Summary

"This trial will use a common PET isotope called Fluorine-18 bound to Choline to study participants with suspected parathyroid adenoma and unclear test results from a standard imaging test."

Who is the study for?

This trial is for people with suspected parathyroid adenoma, which means they have high calcium levels and normal or high parathyroid hormone levels but unclear results from a standard SPECT/CT scan. Participants must be able to consent, have certain liver function test results within acceptable limits, and not be pregnant.Check my eligibility

What is being tested?

The study is testing the effectiveness of using Fluorine-18 (18F) bound to Choline in PET/CT scans for identifying parathyroid adenomas when standard imaging with 99mTc Sestamibi SPECT/CT isn't clear. It's a single-center study where all participants will receive the new imaging technique.See study design

What are the potential side effects?

While specific side effects are not detailed here, PET/CT scans generally may cause discomfort due to injection of the tracer substance and require patients to lie still during imaging. There's also exposure to radiation similar to other medical imaging procedures.

18FCH Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 1 hour

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 1 hour

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 1 hour for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of lesions detected by PET/CT for detecting parathyroid adenomas.

18FCH Trial Design

1Treatment groups

Experimental Treatment

Group I: 18FCH PET/CTExperimental Treatment1 Intervention

Participant receive 18F Fluorocholine injection and approximately 45-60 minutes later receive a low dose CT scan from skull base to mid thighs, followed by a static PET emission scan over the same area.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Andrei IagaruLead Sponsor

15 Previous Clinical Trials

496 Total Patients Enrolled

Andrei Iagaru, MDStudy DirectorStanford University

6 Previous Clinical Trials

442 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current number of individuals involved in this research project?

"Indeed, the details on clinicaltrials.gov show that this investigation is actively searching for candidates. The trial was initially published on September 27, 2023, and last revised on April 15, 2024. Enrollment of approximately a hundred patients will take place at one single site."

Answered by AI

Is the recruitment phase still ongoing for participants in this medical study?

"The current information on clinicaltrials.gov indicates that this research study is actively seeking participants. It was initially posted on September 27, 2023, and last revised on April 15, 2024."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT

Andrei Iagaru 2023. "99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05891769.