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Galantamine for Endothelial Dysfunction
Study Summary
This trial will study whether the drug galantamine can help improve markers of endothelial cell dysfunction in African Americans.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
Media Library
- My blood pressure is often above 140/90 despite taking medication.I use nitrates for my condition.You have taken any experimental medication within the month before the study.I am an African American woman or man.You have a body mass index (BMI) higher than 28, which means you are overweight.My kidney function is reduced.I am a woman who has gone through menopause.I am not pregnant or breastfeeding and use reliable birth control methods.I am not currently taking any medications for memory problems or muscle strength.I am not taking strong medications like ketoconazole or paroxetine, and my liver works well.I have a history of heart issues or have had heart or vascular surgery.I have diabetes with high blood sugar or I'm on diabetes medication.My liver tests (AST or ALT) are more than three times the normal limit.You are allergic to eggs or soy.I am between 18 and 60 years old.You are currently using drugs or alcohol in a harmful way.My heart's electrical signals are partially or completely blocked.I understand the details and risks of the study.I have a history of fainting repeatedly.I have had a serious brain condition like a stroke or mini-stroke.I have had seizures or a history of them.You have a history of abnormal connections in your heart.You have smoked a cigarette within the past month.
- Group 1: Galantamine
- Group 2: Placebo
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What additional experiments have been conducted involving Galantamine?
"Currently, 3 clinical trials for Galantamine are underway. None of these studies have progressed to Phase 3 yet. Nashville is the epicentre of this research with 4 sites currently running experiments on the medication's efficacy."
Is the age eligibility for this trial greater than 20 years old?
"This clinical trial is open to participants between 18 and 60 years of age. For younger or older patients, there are 4 studies designed for the former group and 33 trials specifically tailored to those over 65."
What medical conditions do physicians commonly utilize Galantamine to treat?
"Galantamine is an approved medical intervention for mild dementia of the alzheimer's type, as well as Alzheimer's disease and AD."
Am I eligible to take part in this medical research?
"This clinical trial is seeking 88 individuals aged 18 to 60 who have been diagnosed with endothelial dysfunction. Other requirements include a BMI over 28 and an age range of 18-60 years old."
How many participants are involved in this clinical trial?
"Affirmative. Clinicaltrials.gov confirms that this research effort, initially posted on December 20th 2021, is actively recruiting participants for the trial. 88 people need to be enrolled from 2 distinct clinical sites."
Is enrollment currently open for this clinical investigation?
"As seen on clinicaltrials.gov, this medicinal examination is currently searching for participants and was initially published on December 20th 2021. The trial details have been revised most recently as of December 22nd 2021."
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